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时间:2018-01-02
《amifostine在恶性肿瘤放疗中应用》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、rLrLrLrLrL·774·MODERNONCOLOGY,Apr.2009,VOI.17,NO.4吲NewcombPA,StomrBE.Long—termefficacyofsigmoidoscopyin(6):1593—1598.thereductionofcolorectaIcancerincidenceJ1.JNatlCancerKuznetsovK,LamberR,ReyJF.Narrow—bandimaging:potentialInst,2003,95(8):622—625.andlimitations[J].Endoscopy,
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5、nalysis[J].MRAmJRoentgenol,2003,181Amifostine在恶性肿瘤放疗中的应用驯夏红强,金冶宁AdvancedresearchofAmifostineintheradiotherapytomalignanttumorsXIAHong—qiang,JINYe~ningOncologyDepartmentofRuijinHospitalaffiliatedtoShanghaiJiaotongUniversity,Shanghai200025,China.【Abstract】Radiotherapyisoneofvi
6、taltreatmentstomalignanttumors,butalwaysinevitablycomesupwithsideeffects.Thecellprotectoramifostinecanprotectma~ow,liverandkidneywithoutreducinganti—tumoreficiency.Subcutaneousorintrarectaladministrationismoresuitabletosomepatients.Theprotectioneffecthasdosedependencyandlimi
7、tation,cannotstillimprovethesurvivalrate.【Keywords】amifostine;cellprotector;tumor;radiotherapyModemOncology2009,17(o4):0774—0776【指示性摘要】放疗是治疗恶性肿瘤的主要治疗方法之一,但往往不可避免地出现骨髓抑制等不良反应。细胞保护剂阿米福汀可以对骨髓、肝、肾等起保护作用而不影响抗肿瘤疗效。皮下注射或直肠内给药可能更适合某些病人。其细胞保护作用有一定剂量依赖性和局限性。尚不能影响肿瘤患者的生存率。【关键词】阿米福汀;细胞保
8、护剂;肿瘤;放疗【中图分类号】R730.55【文献标识码】A【文章编号】1672—4992一(2009)04—0774—03放疗,同手术、化疗一样,是
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