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时间:2020-09-16
《七氟醚麻醉下不同剂量舒芬太尼对气管插管时BISNarcotrend的影响.doc》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、七氟醚麻醉下不同剂量舒芬太尼对气管插管时BIS、Narcotrend的影响王荣宁郭曲练刘松华[摘要]目的:观察七氟醚麻醉下应用不同剂量的舒芬太尼,对气管插管时BIS、Narcotrend的影响大小。方法:选择48例妇科患者,ASAⅠ~Ⅱ级,年龄20~49岁,全麻下行择期腹腔镜手术患者,随机分为A、B、C、D四组(n=12)。8%七氟醚吸入诱导(氧流速为6L/min),待患者意识消失后,各组静注罗库溴铵0.6mg/kg(B、C、D组复合应用舒芬太尼,剂量分别为0.25μg/kg、0.5μg/kg、1.0μg/kg,A组给予生理盐水2ml),行控
2、制呼吸,调整氧流速,待各组七氟醚呼气末浓度上升至2.0MAC,维持2min后行气管插管,观察3min后结束实验。连续监测BIS、Narcotrend,同时记录麻醉诱导前(t0)、患者意识消失时(t1)、气管插管前(t2)、气管插管后1min(t3)、气管插管后3min(t4)的血流动力学。结果:四组的BIS、Narcotrend值在患者意识消失时、气管插管前均较麻醉诱导前明显下降(P<0.05);各组气管插管后BIS的上升程度随舒芬太尼剂量的增大而减小,相关有统计学意义(P<0.001);各组Narcotrend值在气管插管前后无明显变化(P
3、>0.05)。结论:在七氟醚麻醉下,舒芬太尼呈剂量依赖性的减小患者气管插管后BIS的上升程度;Narcotrend显示气管插管反应不灵敏。[关键词]七氟醚;舒芬太尼;脑电描记术;麻醉深度TheinfluenceofsulfentanilwithvariousdosesontheBispectralindexandNarcotrendindexduringtheototrachealintubationundertheanestheaiaofsevofluraneWangRongNing,GuoQuLian,LiuSongHua.Departm
4、entofAnesthesiology,XiangyaHospitalofCentralSouthUniversity,ChangshaChina.[Abstract]Objective:ToobservetheinfluenceofsufentanilwithvariousdosesontheBispectralindexandNarcotrendindexduringtheototrachealintubationundertheanesthesiaofsevoflurane.Methods:FortyeightASAⅠ~Ⅱpatient
5、sundergoinggynecologicaloperationswererandomlydividedintofourgroups.GroupA:placebo;GroupB:sufentanil0.25μg/kg;GroupC:0.5μg/kg;GroupD:1.0μg/kg(allinjectedintravenousbeforetheototrachealintubation).TheindexofBispectralandNarcotrendwererecordedcontinuouslyduringtheinductionand
6、ototrachealintubation.Results:TheindicesofBispectralandNarcotrendinallgroupswereallsignificantlowerinthetimepotsoftheLOC(Lossofconsciousness)andpreototrachealintubationthanthoseinpreinduction(P<0.05);thetendencyoftheBispectralindexrisingwasdecreasingwiththeincreasingdoseabo
7、utsufentanilduringtheototrachealintubation(P<0.001);theNarcorendindexinallgroupswerenotsignificantchangablepreandpostototrachealintubation(P>0.05).Conclusion:Undertheanesthesiaofsevoflurane,sufentanildecreasedthetendencyoftheBispectralindexrisingdose-dependently;theNarcotre
8、ndindexwasinsensitiveinthepredictionofthereactiontotheototrachealintubation.[Keywo
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