莫西沙星雾化吸入治疗慢性阻塞性肺疾病合并呼.doc

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1、111莫西沙星雾化吸入治疗慢性阻塞性肺疾病合并呼—医学检验论文【摘要】目的：探讨慢性阻塞性fl市疾病合并呼吸衰竭采用莫西沙星雾化吸入治疗效果。方法：本次选取100例慢性阻塞性肺疾病合并呼吸衰竭患者作研究对象，均为2013年1月・2014年1月笔者所在医院收治，随机分组，观察组50例采用莫西沙星雾化吸入治疗，对照组50例采用沙丁胺醇溶液雾化吸入治疗，对两组临床疗效进行比较。结果：主观症状量表评分两组在治疗前比较差异无统计学意义（P0.05）z治疗后均有下降，但观察组下降幅度明显优于对照组（P0.05X两组均无严重

2、副反应发生，观察组仅口腔黏膜感染2例，对照组胃部不适2例，差异无统计学意义（P0.05结论：慢性阻塞性肺疾病合并呼吸衰竭患者采用莫西沙星雾化吸入治疗，可促使临床症状明显改善，无严重不良事件发生，改善预后价值重大，值得临床广泛推广应用。【关键词】莫西沙星；雾化吸入；慢性阻塞性肺疾病；呼吸衰竭中图分类号R563.8文献标识码B文章编号1674-6805（2014）30-0018-02TheEfficacyofMox讦loxacinInhalationTherapyinPatientswithChronicObst

3、ructivePulmonaryDiseaseandRespiratoryFailure/LIUJian-bin.//ChineseandForeignMedicalResearch,2014,12(30):18-19[Abstract]Objective:ToinvestigatetheeffectofmoxifloxacininhalationtreatmentinCOPDpatientswithrespiratoryfailure.Method:The100patientswithrespiratoryf

4、ailureinpatientswithCOPDwereselectedastheobjectofstudyzbothinourhospitalfromJanuary2013toJanuary2014weretreatedftheywererandomlydividedintotwogroups,50casesintheobservationgroupusedinhalationtherapyusingMoxifloxacin,50casesinthecontrolgroupusedAlbuterolinhal

5、ationsolutiontreatmentztheeffectofthetwogroupswerecompared.Result:Thescoresofsubjectivesymptomsbeforetreatmenthadnosignificantdifferenceintwogroups(P0.05),theyallweredecreasedaftertreatmentzbutthescoresofsubjectivesymptomsdeceasedmoreintheobservationgrouptha

6、nthatinthecontrolgroup(P0.05).Therewerenoseriousadverseeventsoccurredintheobservationgroup,andonly2casesoforalinfections,therewere2casesofstomachupsetinthecontrolgroup,therewasnostatisticaldiffereneeintwogroups(P0.05).Conclusion:Moxifloxacininhalationtherapy

7、inthetreatmentofCOPDpatientswithrespiratoryfailurecancontributetoclinicalimprovementzwithnoseriousadverseevents,inordertoimprovetheprognosticvalueofmaterial,worthyofwiderapplication.【Keywords］Moxifloxacin;Inhalation;Chronicobstructivepulmonarydisease;Respira

8、toryfailureFirst-authorsaddress:XinhuaCountyPeoplesHospital,Xinhua417600#China近年来，环境污染加重，加之人口老龄化社会进程加剧，慢性阻塞性肺疾病(COPD)病发比例显著增多”以气流不完全可逆性受限为特征，病程呈进行性发展,对通气功能造成影响,诱导PaCO2升高，PaO2降低,进而弓I发呼吸衰竭［1］。COPD