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1、踝肱指数(ABI)对糖尿病下肢动脉病变的筛查及其临床应用作者：潘佳秋，张超，田建武单位:佳木斯大学附属第一医院内分泌科，黑龙江佳木斯154003【摘要】目的：探讨踝肱指数(ABI)对糖尿病下肢动脉病变的筛查的意义及其临床应用。方法：取AB1阳性者68例入院治疗患者，随机分为A、B两组，A组为单纯降糖、降血脂治疗，B组除降糖、降血脂外加用丁咯地尔治疗，治疗3个月后再次复查ABI,观察两组治疗前后ABI、血压、空腹血糖(FPG)、餐后2h血糖(2hPG)、总胆固醇(TC)、甘油三脂(TG)变化。结果：1538例糖尿病患者ABI
2、测定阳性者为394例，阳性率为25.6%,ABI阳性患者经下肢动脉彩超证实符合率达100%,ABI阳性者距诊断糖尿病病史1月至2。年，ABI阳性患者病史超过5年者阳性率高达80%。治疗前患者年龄、病程、BMLSBP、FPG、2hPG、TG、TC、ABI差异均无统计学意义,经治疗后A组患者FPG、TG明显下降(P<0.05),SBP、ABI无明显变化。B组患者治疗后较治疗前FPG、TG明显下降(P<0.05),SBP无明显变化，ABI明显改善(P<0.05)o结&:AB1与下肢血管彩超对比相关性好，踝肱指数
3、测量仪既可在诊室中使用，也适用于大规模人群的筛查；应用盐酸丁咯地尔后，临床症状及相关指标均显著优于对照组,ABI明显升高。【关键词】2型糖尿病；踝肱指数；下肢动脉病变；丁咯地尔ValueofanklebrachialindexinscreeningofdiabeteslowerlimbarterydiseaseanditsclinicalapplicationPANJiaqiu,ZHANGChao,TIANJianwu(Endocrinology,theFirstAffiliatedHospitalofJiamusiUni
4、versity,Jiamusi154003,China)Abstract：Objective：Toexplorethesignificanceandthevalueofclinicalapplicationofanklebrachialindex(ABI)indiabetespatientsinscreeningthelowerlimbarterydisease.Methods：Weselected68hospitalizeddiabetespatientswithpositiveABIandrandomlydivided
5、themintotwogroups,GroupAandGroupB.Bothgroupsweregivenhypoglycemic,lipid-loweringtherapy,andButlomedilwasaddedtoGroupB.After3-monthtreatment,theABIwasre-examinedandthechangesofbloodpressure,fastingplasmaglucose(FPG),postprandial2hplasmaglucose(2hPG),cholesteroltota
6、l(TC)andtriglyceride(TG)wereobserved.Results:Therewere394diabetespatientswhoseABIwaspositivein1538cases,thepositiveratebeing25.6%,andtheABIpositivepatientsshowedthecoincidentrateof100%,confirmedbythelowerextremityarterialcolorDoppler.Thehistoiyofdiagnoseddiabetesr
7、angedfrom1monthto20yearsintheABIpositivepatients.TheABIpositivepatientswitha5-yeardiabeteshistoryaccountedfor80%.Therewasnosignificanceinthepatientage,courseofdisease,BMI,SBP,FPG,2hPG,TQTCandtheABIbeforethetreatment.Aftertreatment,theFPGandTGofGroupAweresignifican
8、tlydecreased(P<0.05),withnoobviouschangesintheSBPandABI.TheFPGandTGofGro叩Bweresignificantlydecreasedtoo(P<0.05),withnoobviouschangesintheSBP,andth
