欢迎来到天天文库
浏览记录
ID:55643850
大小:256.32 KB
页数:3页
时间:2020-05-22
《血清 CEA、CA125联合检测在 IV 期肺腺癌患者中的临床意义-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、现代肿瘤医学2014年8月第22卷第8期MODERNONCOLOGY,Aug.2014,VOL22,NO.08·1845·血清CEA、CA125联合检测在IV期肺腺癌患者中的临床意义包金英,周建华,张文杰,王俊莹ClinicalsignificanceofserumCEA,CA125inpatientswithlungadenocarcinomaofstageIVBaoJinying,ZhouJianhua,ZhangWenjie,WangJunyingDepartmentofMedicalOncology,theTh
2、irdAffiliatedHospitalofHarbinMedicalUniversity,HeilongfiangHarbin150081,China.【Abstract】0bjective:TodiscusstheclinicalvalueofserumCEA,CA125levelsinpatientswithlungadenocarci-nomaofstageIV.Methods:All96patientswithlungadenocareinomaofstageIVconfirmedbyclinicalpat
3、hologyintheThirdAfiliatedHospitalofHarbinMedicalUniversitybetween2007and2012werecollectedandreviewed.TheirserumCEA,CA125wasregularlydetectedandtherelationshipofselumCEA,CA125levelsandprognosiswereana—lyzed.Results:ThetotalpositiveratesofserumCEA,CA125in96patient
4、swithlungadenocarcinomawere55.21%,43.75%,andthepositiverateofthecombineddetectionofbothwas68.75%.ThepositiverateofserumCEAandCA125inpatientswiththenumberofdistantmetastaticsitesmorethantwowerehigherthaninpatientswiththeBum—berofdistantmetastaticsiteslessthantwo(
5、P<0.o1,P<0.05).ThepositiverateofserumCEAandCA125inpa-tientswithpleuralmetastasiswerehigherthaninpatientswithoutpleuralmetastasis(P<0.05,P<0.O1).Conelu-sion:SerumCEAandCA125inpatientswithadvancedlungadenoearcinomahaveahigherpositiverate,andtheirser-amlevelsayerel
6、atedtothedegreeoftumorinfiltrationandthepresenceorabsenceofpleuralmetastasis.【Keywords】lungadenocarcinoma;carcino—embryonicantigen;cancerantigen125;tumormarkerModernOncology2014,22(08):1845—1847【摘要】目的:探讨血清CEA及CA125水平在Ⅳ期肺腺癌患者中的临床意义。方法:收集哈尔滨医科大学附属第三医院2007年一2012年间经
7、临床病理和影像学证实的Ⅳ期肺腺癌患者96例,定期对其进行血清CEA、CA125水平检测,了解血清CEA、CA125水平与患者预后的关系。结果:96例肺腺癌患者中血清CEA、CA125的总阳性率分别为55.2l%、43.75%,两者联合检测的阳性率为68.75%。其中,远处转移部位数目>2个的患者血清CEA及CA125阳性率均高于转移部位数目≤2个的患者,差异有统计学意义(P<0.01,P<0.05)。有胸膜转移的患者血清CEA、CA125阳性率均高于无胸膜转移的患者,差异有统计学意义(P<0.05,P<0.叭)。结论:
8、血清CEA和CA125联合检测在晚期肺腺癌患者中有较高的阳性率,且其血清水平与肿瘤浸润程度和有无胸膜转移相关。【关键词】肺腺癌;癌胚抗原;糖类抗原CA125;肿瘤标记【中图分类号】R734.2【文献标识码】ADOI:10.3969/j.issn.1672—4992.2014.08.30【文章编号】1672—4992一(2014)0
此文档下载收益归作者所有