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时间:2020-05-18
《外科微创手术治疗心房颤动对左心房功能的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、2015正6月首都医科大学学报June.2015第36卷第3期JournalofCapitalMedicalUniversityVoL36No.3[doi:10.3969/j.issn.1006-7795.2015.03.007]·心脏大血管外科领域前沿进展·外科微创手术治疗心房颤动对左心房功能的影响张振华张海波韩建成孟旭韩杰李岩王刚(首都医科大学附属北京安贞医院心脏外科9病房北京市心肺血管疾病研究所,北京100029)【摘要】目的通过检测阵发性心房颤动(以下简称房颤)患者行外科微创手术治疗前后左心房功能的变化,探讨该手术对左心房功能的影响。方法选择2012年10月至20
2、14年6月在首都医科大学附属北京安贞医院心外科九病房行外科微创手术(胸腔镜辅助射频消融、左心耳切除及Marshall韧带离断)治疗的阵发性房颤患者52例,分别于术前(窦性心律时)、术后7d及术后3个月,应用实时经胸三维超声心动图测量左心房功能,进行统计学分析。结果1)消融术后6例患者房颤复发,余46例完成研究,手术转窦率为88.5%(46/52)。无手术相关严重合并症发生,术后3个月所有患者均未发生栓塞事件。左心耳切除成功率为77%(40/52,左心耳残端3、较术前逐渐减小,差异有统计学意义(P<0.001);左心房最小容积(1eftatrialminimumvolume,LAVmin)术后3个月较术前、术后7d均减小,差异有统计学意义(P<0.001);左心房总排空分数(1eftatrialemptyingfraction,LAEF)术后7d较术前、术后3个月低,差异有统计学意义(P<0.001),术前、术后3个月差异无统计学意义(P=0.235);左心房被动排空分数(1eftatrialpassiveejectionfraction,LAPEF)术后7d、术后3个月较术前减低,差异有统计学意义(P<0.05);左心房主动排4、空分数(1eftatrialactiveejectionfraction,LAAEF)术后3个月较术前、术后7d增强,术后7d较术前减弱,差异有统计学意义(P<0.05)。A峰流速术后3个月较术后7d增强,差异有统计学意义(P<0.001),术后3个月与术前差异无统计学意义(P=0.497)。结论1)外科微创手术是治疗阵发性房颤安全、有效的方法,能有效的恢复患者的窦性心律、预防栓塞事件的发生。2)外科微创手术治疗阵发性房颤有利于左心房逆重塑及功能增强,其远期影响有待进一步随访研究。【关键词】心房颤动;心房功能;外科手术;微创性【中图分类号】R541.7Effectofmi5、nimallyinvasivesurgeryonleftatrialfunctioninatrialfibrillationpatientsZhangZhenhua,ZhangHaibo,HanJiancheng,MengXu,HanJie,LiYan,WangGang(CardiacSurgeryWardNo.9,BeijingAnzhenHospital,CapitalMedicalUniversity;BeijingInstituteofHeart,LungandBloodVesselDiseases,Beijing100029,China)【Abstract】Ob6、jectiveTocomparetheleftatrialfunctioninparoxysmalatrialfibrillationpatientsbe~reandafterundergoingminimallyinvasivesurgery.MethodsConsecutive52patientswithparoxysmalatrialfibrillationwhounderwentminimallyinvasivesurgery(pulmonaryveinisolation,leftatrialappendageexcision,ligamentofMarshall7、resection)inAnzhenHospitalfromOctober2012toJune2014wereenrolledintothisstudy.Leftatrialfunctionwasmeasuredbyreal—timethree-dimensionaleehocardiographybeforeoperation,7daysand3monthsafteroperation.Results1)Eachofthe52patientssuccessfullyunderwentthesurgery.Neitherser
3、较术前逐渐减小,差异有统计学意义(P<0.001);左心房最小容积(1eftatrialminimumvolume,LAVmin)术后3个月较术前、术后7d均减小,差异有统计学意义(P<0.001);左心房总排空分数(1eftatrialemptyingfraction,LAEF)术后7d较术前、术后3个月低,差异有统计学意义(P<0.001),术前、术后3个月差异无统计学意义(P=0.235);左心房被动排空分数(1eftatrialpassiveejectionfraction,LAPEF)术后7d、术后3个月较术前减低,差异有统计学意义(P<0.05);左心房主动排
4、空分数(1eftatrialactiveejectionfraction,LAAEF)术后3个月较术前、术后7d增强,术后7d较术前减弱,差异有统计学意义(P<0.05)。A峰流速术后3个月较术后7d增强,差异有统计学意义(P<0.001),术后3个月与术前差异无统计学意义(P=0.497)。结论1)外科微创手术是治疗阵发性房颤安全、有效的方法,能有效的恢复患者的窦性心律、预防栓塞事件的发生。2)外科微创手术治疗阵发性房颤有利于左心房逆重塑及功能增强,其远期影响有待进一步随访研究。【关键词】心房颤动;心房功能;外科手术;微创性【中图分类号】R541.7Effectofmi
5、nimallyinvasivesurgeryonleftatrialfunctioninatrialfibrillationpatientsZhangZhenhua,ZhangHaibo,HanJiancheng,MengXu,HanJie,LiYan,WangGang(CardiacSurgeryWardNo.9,BeijingAnzhenHospital,CapitalMedicalUniversity;BeijingInstituteofHeart,LungandBloodVesselDiseases,Beijing100029,China)【Abstract】Ob
6、jectiveTocomparetheleftatrialfunctioninparoxysmalatrialfibrillationpatientsbe~reandafterundergoingminimallyinvasivesurgery.MethodsConsecutive52patientswithparoxysmalatrialfibrillationwhounderwentminimallyinvasivesurgery(pulmonaryveinisolation,leftatrialappendageexcision,ligamentofMarshall
7、resection)inAnzhenHospitalfromOctober2012toJune2014wereenrolledintothisstudy.Leftatrialfunctionwasmeasuredbyreal—timethree-dimensionaleehocardiographybeforeoperation,7daysand3monthsafteroperation.Results1)Eachofthe52patientssuccessfullyunderwentthesurgery.Neitherser
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