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《活血祛风除湿中药足浴联合口服甲钴胺片治疗糖尿病周围神经病变临床观察.pdf》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。
1、·22·ChineseJournalofInformationonTCMDec.2014Vol.21No.12活血祛风除湿中药足浴联合口服甲钴胺片治疗糖尿病周围神经病变临床观察张毅,张敏上海市中医医院内分泌科,上海200071摘要：目的探讨活血祛风除湿中药足浴联合口服甲钴胺片治疗糖尿病周围神经病变(DPN)的临床疗效。方法采用随机数字表法将将65例2型糖尿病患者随机分为2组,均行糖尿病饮食控制、运动及教育,保持既往降糖方案,高血压者予硝苯地平控释片。对照组同时予甲钴胺片口服,治疗组在对照组基础上加用活血祛风除湿中药足浴。治疗12周。观察2组
2、治疗前后临床症状积分、Toronto临床评分变化,测定肢体正中神经、腓总神经的运动传导速度(MNCV)及感觉传导速度(SNCV)。结果2组治疗后临床症状评分、Toronto临床评分及正中神经、腓总神经MNCV、SNCV均显著降低(P＜0.05,P＜0.01)。治疗组中医证候疗效总有效率为81.81%(27/33),对照组为65.62%(21/32),2组比较差异有统计学意义(P＜0.05)。治疗组西医疗效总有效率为84.84%(28/33),对照组为62.50%(20/32),2组比较差异有统计学意义(P＜0.05)。结论活血祛风除湿中药足
3、浴联合甲钴胺片口服治疗DPN安全有效。关键词：中药足浴；甲钴胺片；糖尿病周围神经病变DOI：10.3969/j.issn.1005-5304.2014.12.007中图分类号：R259.872文献标识码：A文章编号：1005-5304(2014)12-0022-03ClinicalObservationinTreatmentofDiabeticPeripheralNeuropathybyBlood-activatingandQufengchushiChineseMedicineLavipeditumwithMecobalaminTablet
4、sZHANGYi,ZHANGMin(EndocrinologyDepartment,ShanghaiTraditionalChineseMedicineHospital,Shanghai200071,China)Abstract：ObjectiveToobservetheclinicalefficacyintreatmentondiabeticperipheralneuropathy(DPN)byChinesemedicinelavipeditumofblood-activatingandQufengchushiwithmecobalami
5、ntablets.Methods65diabeticpatientswererandomlydividedinto2groups.Thetwogroupswerebothundertakingthediabetesdietcontrol,exercise,diabeteseducationandmaintainingprevioushypoglycemicprogram.ThepatientswithhypertensioncouldtakenifedipineGITS.Patientsincontrolgrouponlyreceivedm
6、ecobalamintablet.PatientsintreatmentgroupreceivedthesamemedicationandalsolavipeditumwithBlood-activatingandQufengchushitraditionalChinesemedicinefor12weeks.Clinicalsymptomscore,Torontoclinicalscore,motornerveconductionvelocity(MNCV)andsensoryconductionvelocity(SNCV)ofmedia
7、nnerveandperonealnervewereperformedbeforeandafterthestudy.ResultsAftertreatment,themeanvaluesforclinicalsymptomscore,Torontoclinicalscore,MNCVandSNCVofmediannerveandperonealnerveofthetweogroupswereallsignificantlydecreased(P＜0.05,P＜0.01).ThevaluesforTCMclinicalsyndromesint
8、reatmentgroupwas81.81%(27/33),andthatinthecontrolgroupwas65.62%(21/32),withsignificantdif
