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时间:2020-05-15
《红细胞体积分布宽度对脓毒症急性肾损伤患者预后的评估价值.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、海南医学2014年1O月第25卷第2O期Hain~rlMedJ,Oct.2014,Voi.25,No.20doi:10.3969/j.issn.1003—6350.2014.20.1184·论著·红细胞体积分布宽度对脓毒症急性肾损伤患者预后的评估价值范金强。,范银强,李振军(1刑门市第二人民医院心胸外科,湖北荆门448001;2.深圳龙岗区人民医院重症医学科,广东深圳524000)【摘要】目的探讨红细胞体积分布宽度0mw)与脓毒症急性肾损伤(AKI)患者预后的关系。方法选取2011年3月至2013年12
2、月入住我院ICU确诊为脓毒症AKI患者89例,按其预后分为死亡组和存活组,分别测定动脉血乳酸(Lac)、血肌酐(scO、血小板(PLT)及RDW水平,同时进行急性生理学及慢性健康评估(APACHEII)评分。选取20例健康体检者作为对照组。结果存活组RDW水平显著低于死亡组,差异具有统计学意义(存活组VS死亡组,t=5.16,P<0.01);存活组动脉血乳酸水平显著低于死亡组(存活组vs死亡组,t=12.88,P<0.O1);存活组PLT水平高于死亡组(存活组VS死亡组,t=1.99,P<0.05);存
3、活组APACHEII评分低于死亡组(存活组VS死亡组,t-=4.00,P4、Yin-qiang212Zhen1.1.DepartmentofCardio—ThoracicSurgery,theSecondPeopleHospitalofJingmen,Jingmen448000,Hubei,CHINA;2.DepartmentofIntensiveMedicine,LonggangDistrictPeopleHospitalofShenzhen,Shenzhen51812~Guangdong,CHINA【Abstract】ObjectiveToinvestigatetherel5、ationshipbetweenredbloodcelldistributionwidth(RDW)andtheprognosisofacutekidneyinjury(AKDassociatedwitllsepsis.MethodsEighty-ninepatien~diagnosedasAKIassociatedwithsepsisinICUofourhospimlduringMarch2011toDecember2013wereselectedanddividedintosur-vivalgrou6、p(,l=:55)anddeathgroup(,l=34).Thelevelsofa~erialbloodlactate(Lac),serulncreatinine(sCr),redbloodcelldistributionwidthfRDW)andbloodplatelet(PLT)weremeasured.Moreover,theacutephysiologyandchronichealthevaluationscoring(APACHEII)werecollected.Meanwhile,twen7、tyhealthyvolunteerswereenrolledasthecontrolgroup(2O).ResultsCompared、)l,imthesurvivalgroup,theexpressionlevelsofLac,RDWandAPACHEIIsignificantlyincreased(Lac,t=12.88,P<0.01;RDWt=5.16,P<0.01;APACHEIIt--4.00,P<0.05).However,PLTsignificantlydecreasedindeathg8、roup(survivalgroupVSdeathgroup,t=1.99,P
4、Yin-qiang212Zhen1.1.DepartmentofCardio—ThoracicSurgery,theSecondPeopleHospitalofJingmen,Jingmen448000,Hubei,CHINA;2.DepartmentofIntensiveMedicine,LonggangDistrictPeopleHospitalofShenzhen,Shenzhen51812~Guangdong,CHINA【Abstract】ObjectiveToinvestigatetherel
5、ationshipbetweenredbloodcelldistributionwidth(RDW)andtheprognosisofacutekidneyinjury(AKDassociatedwitllsepsis.MethodsEighty-ninepatien~diagnosedasAKIassociatedwithsepsisinICUofourhospimlduringMarch2011toDecember2013wereselectedanddividedintosur-vivalgrou
6、p(,l=:55)anddeathgroup(,l=34).Thelevelsofa~erialbloodlactate(Lac),serulncreatinine(sCr),redbloodcelldistributionwidthfRDW)andbloodplatelet(PLT)weremeasured.Moreover,theacutephysiologyandchronichealthevaluationscoring(APACHEII)werecollected.Meanwhile,twen
7、tyhealthyvolunteerswereenrolledasthecontrolgroup(2O).ResultsCompared、)l,imthesurvivalgroup,theexpressionlevelsofLac,RDWandAPACHEIIsignificantlyincreased(Lac,t=12.88,P<0.01;RDWt=5.16,P<0.01;APACHEIIt--4.00,P<0.05).However,PLTsignificantlydecreasedindeathg
8、roup(survivalgroupVSdeathgroup,t=1.99,P
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