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《醋酸钠林格注射液纠正失血性休克代谢性酸中毒的临床效果.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、第32卷第2期医学研究与教育V.01.32No.22015年4月MedicalResearchandEducationApr.,2015本文引用:刘冬,曹志然,刘斌.醋酸钠林格注射液纠正失血性休克患者代谢性酸中毒的临床效果Ⅱ】医学研究与教育,2015,32(2):50—53.醋酸钠林格注射液纠正失血性休克代谢性酸中毒的临床效果刘冬,曹志然’。刘斌(1.河北大学基础医学院,河北保定071000;2.中国人民解放军第二五二医院麻醉科,河北保定071000)摘要:目的比较醋酸钠林格注射液与乳酸钠林格注射液对失血性
2、休克患者代谢性酸中毒的影响。方法失血性休克患者50例,按随机数字表法分为醋酸钠林格注射液组(A组)、乳酸钠林格注射液组(L组),每组25例。观察诱导前(To),诱导后1h(T)、2h(T)、3h(T)、4h(T4)患者血液pH值、血乳酸值(LAC)、碱剩余(BE),HC0一值及NaHCO用量。结果2组患者在ASA分级、手术时间、术中输入试验晶体液量、失血量这5项指标差异均无统计学意义(P>0.05)。A组在L时间点较L组pH值显著改善(P3、L组T2、、T4时间点LAC值较Tn点明显升高(P4、-490X(2015)02-0050-04Analysisoftheclinicalefectofacetateringersincorrectingmetabolicacidosisinpatien~withhemorrhagicshockLIUDong。,CAOZhiran,LIUBinfj.CollegeofBasicMedicalSciencesofHebeiUniversity,Baoding071000,China,"2.DepartmentofAnesthesiology,No.252Hosp5、italofPLA.Baoding071004China)Abstract:ObjectiveTocomparetheeffectsofacetateringerssolutionandlactatedringerssolutiononmetabolicacidosisinpatientswithhemorrhagicshock.Methods50patientswithhemorrhagicshockweredividedequallyinto2groupsrandomly(n=25):theacetat6、eringerssolution(groupA)andlactatedringersgroup(groupL).ChangesofarterialbloodgasandvolumeofNaHC03beforeand1,2,3,4hafterinductionrespectivelywereobserved.ResultsTherewerenostatisticsdifferenceintheASAgrade,operationtime,thevolumeoftransfusionduringoperatio7、nandhemorrhagevolumeofbothgroups(P>0.05).pHingroupAchangedattimepointofT3respectivelycomparedtogroupL(P<0.05).Serumlactatelevel(LAC)decreasedatT2comparedtoT0timeingroupA(尸<0.05).LAClevelincreasedatT2,T3,T4comparedtoT0timeingroupL(P<0.05).LAClevelingroupLin8、creasedattimepointofT2,T3,T4comparedtogroup收稿13期:2015—03—07作者简介:刘冬(1982一),女,河北保定人,主治医师,主要从事麻醉药理学研究。通信作者:曹志然(1963一),女,河北景县人,教授,硕士生导师,主要从事免疫药理学研究。E—mail:caozhiran@163.com50第2期刘冬等:醋酸钠格注射液纠正失血『生休克代谢性酸中毒的临床效果2015年
3、L组T2、、T4时间点LAC值较Tn点明显升高(P4、-490X(2015)02-0050-04Analysisoftheclinicalefectofacetateringersincorrectingmetabolicacidosisinpatien~withhemorrhagicshockLIUDong。,CAOZhiran,LIUBinfj.CollegeofBasicMedicalSciencesofHebeiUniversity,Baoding071000,China,"2.DepartmentofAnesthesiology,No.252Hosp5、italofPLA.Baoding071004China)Abstract:ObjectiveTocomparetheeffectsofacetateringerssolutionandlactatedringerssolutiononmetabolicacidosisinpatientswithhemorrhagicshock.Methods50patientswithhemorrhagicshockweredividedequallyinto2groupsrandomly(n=25):theacetat6、eringerssolution(groupA)andlactatedringersgroup(groupL).ChangesofarterialbloodgasandvolumeofNaHC03beforeand1,2,3,4hafterinductionrespectivelywereobserved.ResultsTherewerenostatisticsdifferenceintheASAgrade,operationtime,thevolumeoftransfusionduringoperatio7、nandhemorrhagevolumeofbothgroups(P>0.05).pHingroupAchangedattimepointofT3respectivelycomparedtogroupL(P<0.05).Serumlactatelevel(LAC)decreasedatT2comparedtoT0timeingroupA(尸<0.05).LAClevelincreasedatT2,T3,T4comparedtoT0timeingroupL(P<0.05).LAClevelingroupLin8、creasedattimepointofT2,T3,T4comparedtogroup收稿13期:2015—03—07作者简介:刘冬(1982一),女,河北保定人,主治医师,主要从事麻醉药理学研究。通信作者:曹志然(1963一),女,河北景县人,教授,硕士生导师,主要从事免疫药理学研究。E—mail:caozhiran@163.com50第2期刘冬等:醋酸钠格注射液纠正失血『生休克代谢性酸中毒的临床效果2015年
4、-490X(2015)02-0050-04Analysisoftheclinicalefectofacetateringersincorrectingmetabolicacidosisinpatien~withhemorrhagicshockLIUDong。,CAOZhiran,LIUBinfj.CollegeofBasicMedicalSciencesofHebeiUniversity,Baoding071000,China,"2.DepartmentofAnesthesiology,No.252Hosp
5、italofPLA.Baoding071004China)Abstract:ObjectiveTocomparetheeffectsofacetateringerssolutionandlactatedringerssolutiononmetabolicacidosisinpatientswithhemorrhagicshock.Methods50patientswithhemorrhagicshockweredividedequallyinto2groupsrandomly(n=25):theacetat
6、eringerssolution(groupA)andlactatedringersgroup(groupL).ChangesofarterialbloodgasandvolumeofNaHC03beforeand1,2,3,4hafterinductionrespectivelywereobserved.ResultsTherewerenostatisticsdifferenceintheASAgrade,operationtime,thevolumeoftransfusionduringoperatio
7、nandhemorrhagevolumeofbothgroups(P>0.05).pHingroupAchangedattimepointofT3respectivelycomparedtogroupL(P<0.05).Serumlactatelevel(LAC)decreasedatT2comparedtoT0timeingroupA(尸<0.05).LAClevelincreasedatT2,T3,T4comparedtoT0timeingroupL(P<0.05).LAClevelingroupLin
8、creasedattimepointofT2,T3,T4comparedtogroup收稿13期:2015—03—07作者简介:刘冬(1982一),女,河北保定人,主治医师,主要从事麻醉药理学研究。通信作者:曹志然(1963一),女,河北景县人,教授,硕士生导师,主要从事免疫药理学研究。E—mail:caozhiran@163.com50第2期刘冬等:醋酸钠格注射液纠正失血『生休克代谢性酸中毒的临床效果2015年
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