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时间:2020-05-07
《复合蛋白营养剂治疗乙型肝炎肝硬化患者营养状态及肝功能的变化-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·466·肝脏病杂志2014年9月第17卷第5期JPracHepatol,Sep.20⋯14.Vol110.5·肝病营养·复合蛋白营养剂治疗乙型肝炎肝硬化患者营养状态及肝功能的变化陈婷,于静,张建民【摘要】目的观察复合蛋白营养剂对存在蛋白质一能量营养不良(PEM)的乙型肝炎肝硬化患者营养状态及肝功能的影响。方法选择存在PEM的乙型肝炎肝硬化患者40例,基线均不存在相关并发症,分为复合蛋白营养剂组25例及对照组15例。复合蛋白营养剂组给予新型夜间加餐(原味酸牛奶200g+复合蛋白营养剂15g)配合一般综合治
2、疗,对照组给予一般综合治疗;观察两组患者的血清白蛋白、前白蛋白、淋巴细胞计数,并记录患者发生并发症的情况。结果在两组患者基线资料具有可比性的情况下,与治疗前相比,复合蛋白营养剂组患者血清白蛋白、前白蛋白、淋巴细胞计数明显上升,在6周末,对照组患者白蛋白为(30.2±3.2)geL,显著低于治疗组[(33.6±3.7)g/L,P3、,显著低于治疗组[(1.36±0.26)×109/L,P4、fpatientswithhepatitisBvirus—relatedcirrhosisChen,YuJing,ZhangJianmin.DepartmentofGastroenterology,HenanProvincialHospital,Zhengzhou450003,HenanProvince,China【Abstract】0bjectiveToinvestigatetheefectofcompoundproteinnutritionagentonnutritionalstatusandlive5、rfunctionofhepatitisBvirus(HBV)-relatedcirrhoticpatientswithprotein—energymalnutrition(PEM).MethodsFortyHBV-relatedcirrhoticpatientswithPEMwereenroledandnoothercomphcationsexistedatthebaseline.Patientswerethendividedintoproteinnutritionagentgroup(interven6、tiongroup,25cases)andcontrolgroup(15Cases).PatientsintheinterventiongroupwereVeneveningsnack(200gyoghourtand15gcompoundproteinnutritionagent)withgeneralcomprehensivetreatment,whilepatientsinthecontrolgrouponlyreceivedgeneraltreatment.Serumalbumin,prealbum7、inandlymphocytecountweretestedandcomplicationswererecordedaswel1.ResultsBaselinecharacteristicsofthetwogroupswerecomparable,andtheSeYUmalbumin,prealbuminandlymphocytecountinpatientsofinterventiongroupweresignificantlyincreasedthanthatofthecontrols.At6week8、s,thealbumin,prealbuminandlymphocytescountsinpatientsofthecontrolgroupwere(30.2±3.2)g/L,(122.10~24)g,Land(1.08.10士O_31)xlOg/L,significantlylowerthantheinterventiongroup[(33.6±3.7)g/L,(159.0.6±30.4)eLand(1.36±0.26)×1
3、,显著低于治疗组[(1.36±0.26)×109/L,P4、fpatientswithhepatitisBvirus—relatedcirrhosisChen,YuJing,ZhangJianmin.DepartmentofGastroenterology,HenanProvincialHospital,Zhengzhou450003,HenanProvince,China【Abstract】0bjectiveToinvestigatetheefectofcompoundproteinnutritionagentonnutritionalstatusandlive5、rfunctionofhepatitisBvirus(HBV)-relatedcirrhoticpatientswithprotein—energymalnutrition(PEM).MethodsFortyHBV-relatedcirrhoticpatientswithPEMwereenroledandnoothercomphcationsexistedatthebaseline.Patientswerethendividedintoproteinnutritionagentgroup(interven6、tiongroup,25cases)andcontrolgroup(15Cases).PatientsintheinterventiongroupwereVeneveningsnack(200gyoghourtand15gcompoundproteinnutritionagent)withgeneralcomprehensivetreatment,whilepatientsinthecontrolgrouponlyreceivedgeneraltreatment.Serumalbumin,prealbum7、inandlymphocytecountweretestedandcomplicationswererecordedaswel1.ResultsBaselinecharacteristicsofthetwogroupswerecomparable,andtheSeYUmalbumin,prealbuminandlymphocytecountinpatientsofinterventiongroupweresignificantlyincreasedthanthatofthecontrols.At6week8、s,thealbumin,prealbuminandlymphocytescountsinpatientsofthecontrolgroupwere(30.2±3.2)g/L,(122.10~24)g,Land(1.08.10士O_31)xlOg/L,significantlylowerthantheinterventiongroup[(33.6±3.7)g/L,(159.0.6±30.4)eLand(1.36±0.26)×1
4、fpatientswithhepatitisBvirus—relatedcirrhosisChen,YuJing,ZhangJianmin.DepartmentofGastroenterology,HenanProvincialHospital,Zhengzhou450003,HenanProvince,China【Abstract】0bjectiveToinvestigatetheefectofcompoundproteinnutritionagentonnutritionalstatusandlive
5、rfunctionofhepatitisBvirus(HBV)-relatedcirrhoticpatientswithprotein—energymalnutrition(PEM).MethodsFortyHBV-relatedcirrhoticpatientswithPEMwereenroledandnoothercomphcationsexistedatthebaseline.Patientswerethendividedintoproteinnutritionagentgroup(interven
6、tiongroup,25cases)andcontrolgroup(15Cases).PatientsintheinterventiongroupwereVeneveningsnack(200gyoghourtand15gcompoundproteinnutritionagent)withgeneralcomprehensivetreatment,whilepatientsinthecontrolgrouponlyreceivedgeneraltreatment.Serumalbumin,prealbum
7、inandlymphocytecountweretestedandcomplicationswererecordedaswel1.ResultsBaselinecharacteristicsofthetwogroupswerecomparable,andtheSeYUmalbumin,prealbuminandlymphocytecountinpatientsofinterventiongroupweresignificantlyincreasedthanthatofthecontrols.At6week
8、s,thealbumin,prealbuminandlymphocytescountsinpatientsofthecontrolgroupwere(30.2±3.2)g/L,(122.10~24)g,Land(1.08.10士O_31)xlOg/L,significantlylowerthantheinterventiongroup[(33.6±3.7)g/L,(159.0.6±30.4)eLand(1.36±0.26)×1
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