T2WI、DWI 及梯度回波同、反相位成像检测乙肝肝硬化背景小肝癌的定量研究-论文.pdf

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1、·868·临床放射学杂志2014年第33卷第6期腹部放射学T2WI、DWI及梯度回波同、反相位成像检测乙肝肝硬化背景小肝癌的定量研究张学琴，陆健，王霄英，缪小芬，张涛，梁宏伟，黄爱娜，丁丁，姜吉锋，方艳，杨雪飞【摘要】目的定量评估T：wI、扩散加权成像(DWI)、同相位(IP)及反相位(OP)成像对乙肝肝硬化背景小肝癌(SHCC)的检测能力。方法42例乙肝肝硬化患者共46个经病理证实的SHCC病灶，均行TWI、DWI、IP及OP扫描。分析病灶在4个序列上的信号特征，测量SHCC及肝实质背景在4个序列上的sI及SD噪声，比较T，WI、DWI、

2、IP及OP对乙肝肝硬化背景SHCC的检出率并定量分析上述4个序列检测SHCC的信号噪声比(SNR)及对比噪声比(CNR)。结果T：WI、DWI、IP及OP对乙肝肝硬化背景SHCC的检出率差异无统计学意义(P>0．05)。SNR：DWI>IP>OP>T2WI，各组间SNR差异均有统计学意义(P<0．05)；CNR：DWI>T，WI、IP、OP，DW1分别与TWI、IP、OP比较差异均有统计学意义(P<0．05)，T2WI、IP、OP3组间差异无统计学意义(P>0．05)。结论DWI检测乙肝肝硬化背景SHCC的SNR和CNR最高，显著优于TWI

3、、IP和OP，但是4个序列对SHCC的检出率并无显著差异。【关键词】肝细胞肝癌肝硬化磁共振成像T2WeightedImaging，DifusionWeightedImaging，GradientRecalledEchoInPhaseandOpposedphaseforQuantitativeDetectionofSmallHepatocellularCarcinomainPatientswithHepatitisBInducedCirrhosis：AComparisonStudyZHANGXueqin，LUJian，WANGXiaoying

4、，eta1．DepartmentofRadiology，theThirdPeoplegHospitalofNantong，JiangsuProvince226006，P．R．China【Abstract】ObjectiveToassessT2weightedimaging(T2wI)，Diffusionweightedimaging(DWI)，Gradientrecalledecho—Inphase(IP)andOpposedphase(OP)forquantitativedetectionofsmallhepatocellularcarc

5、inomas(SHCC)inpa—tientswithhepatitisBinducedcirrhosis．MethodsAtotalof42hepatitisBinducedcirrhoticpatientswith46SHCCwhichwerepathologicallyconfirmed，underwentT2WI，DWI，IPandOPMRscanning．ThemanifestationsofSHCConthefoursequenceswereanalyzed，thesignalintensity(SI)ofSHCCandlive

6、rparenchymaonthefoursequencesweremeas—ured，thestandarddeviationofnoise(SDnoise)，thedetectionrate，SNRandCNRofSHCConT，WI。DWI．IPandOPwerecompared．Results(1)Therewerenostatisticallysignificantdifference(P>0．05)ofdetectionratesamongT2wI，DWI，IPandOP．(2)ForSNR：DWI>IP>OP>T2wI，whic

7、hhadstatisticallysignificantdifference(P<0．05)a—mongT2WI，DWI，IPandOP；ForCNR：DWI>T2WI，IP，OP，whichhadstatisticallysignificantdifferences(P<0．05)betweenDWIandT2wI，IP，OP，respectively，nostatisticallysignificantdifference(P>0．05)couldbedetectedamongT2WI，IPandOP．ConclusionTheSNRa

8、ndCNRwasthehighestonDWIamongalltheaequences．whichwassupe—riortoT2WI，IPandOP，butthedetecti