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ID:54600086
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时间:2020-05-03
《医学常用浓度(或含量)表示法.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、第5期丘奕文.等.多中心回顾性队列研究中医药对中晚期原发性肝癌生存期的影响705InfluenceofChineseMedicineonLifeSpanofMiddle-latePrimaryHepaticCarcinomaPatients:AMulticenterRetrospectiveCohortStudyQIUYiwen,LINLizhu,HUANGXuewu,WANGShutanf,LIMe(1.ZhongshanHospitalAfiliatedtoGuangzhouUniversi
2、tyofChineseMedicine,Zhongshan528400Guangdong,China;2.Dept.ofNeoplasma,theFirstAfiliatedHospitalofGuangzhouUniversityofChineseMedicine,theCooperationGroupLeaderofNationalKeySpecialityforTraditionalChineseMedicalNeoplasma,Guangzhou510405Guangdong,China
3、)Abstract:ObjectiveToinvestigatetheinfluenceofChinesemedicine(CM)treatmentonlifespanofmiddle—lateprimaryhepaticcarcinoma(PHC)patients.ResultsAmulticenterretrospectivecohortstudywascarried0utin489PHCpatientsatthestagesof11b,IIIaand111bcollectedfrom15d
4、omestichospitals.WithCMtreatmentastheexposurefactor.theenrolledpatientsweredividedintoCMgroup,westernmedicine(WM)groupandtheCM—WMcombinationgroup.Themainoutcomesincludedmediansurvivaltime(MST)andsurvivalrate.andtheeffectsofCMtreatmentandminimallyinva
5、sivetherapyOilMSTwereobserved.ResultsHalf—a—Yearsurvivalrate.one—yearsurvivalrateandtwo—yearsurvivalratewere50%,9%,1%inCMgroup,70%,30%,6%inCM-WMcombinationgroup,and50%,10%0%inWMgroup.respectivelv.ThesurvivalratesinCM—WMcombinationgroupdifferedfromtho
6、seinCMgroupandWMgroup(P<0.01),butthedifferencesofsurvivalratesbetweenCMgroupandWMgroupwereinsignificant(P>0.o5).MSTatthestagesofⅡb,ma,mbinCM—WMgroupwasobviouslyprolongedascomparedwiththeothertwogroups(P<0.01),andMSTatthestagesofllIa,11binCMgroupwasal
7、soobviouslyprolongedascomparedwithWMgI.0up(P<0.05).ThedifferenceofMSTatthestageof11bwasinsignificantbetweenCMgroupandWMgroup(P>0.05).CMtreatmentandminimallyinvasivetherapywereeffectiveonprolongingthesurvivaltimeofPHCpatients(P<0.01).TheresultsofCOXre
8、gressionanalysisshowedthatKarnofskyscores,CMtreatmentandminima11vinvasivetherapywerethepreventivefactorsfortheprognosis.ConclusionCM—WMc0mbinationgrouphasthebestlong—termtherapeuticeffect.CM—WMcombinationtreatmentisefectiveonincreasingMSTandlong—term
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