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1、莫西沙星雾化吸入治疗慢阻肺合并呼吸衰竭患者的疗效分析中铁二局中心医院内四科四川成都610031【摘要】目的：研究莫西沙星雾化吸入治疗慢阻肺合并呼吸衰竭患者的疗效。方法：选择來自我院成2015年7月・2016年7月慢阻肺合并呼吸衰竭患者80例。随机分组，参照组采用沙丁胺醇进行雾化吸入治疗，干预组在参照组基础上加用莫西沙星雾化吸入治疗。比较两组患者治疗效果。结果：干预组相较于参照组慢阻肺合并呼吸衰竭治疗总有效率更高，PV0.05；干预组相较于参照组呼吸困难、咳嗽、发热、肺部啰音消失时间更短，PV0.05；用药前两组C反应蛋白、氧分压、二氧
2、化碳分压、用力肺活量相似，P>0.05；用药2周干预组相较于参照组C反应蛋白、氧分压、二氧化碳分压、用力肺活量改善更显著，P<0.05o结论：莫西沙星雾化吸入治疗慢阻肺合并呼吸衰竭患者的疗效确切，可有效改善患者临床症状，改善其肺功能，减轻机体炎症水平，改善血气分析指标,值得推广。【关键词】莫西沙星;雾化吸入;慢阻肺合并呼吸衰竭患者;沙丁胺醇；炎症水平EffectofMoxifloxacinAerosolinhalationonChronicObstructivePulmonaryDiseaseComplicatedwithRespir
3、atoryFailureZhuYaChinaRailwaytwoBureauCentralHospital,Chengdu,Sichuan610031【Abstract]Objective:Tostudytheeffectsofinhalationofmox讦loxacinintreatmentofpatientswithchronicobstructivepulmonarydiseasewithrespiratoryfailure.Methods:80casesofchronicobstructivepulmonarydisease
4、complicatedwithrespiratoryfailurewereselectedinourhospitalfromJuly2015toJuly2016.Randomized,controlgroupusingsalbutamolatomizationinhalationtreatment,theinterventiongroupinthecontrolgroupbasedontheuseofmoxifloxacinatomizationinhalationtherapy・Comparisonoftwogroupsofpati
5、entswiththerapeuticeffect・Results:theinterventiongroupcomparedwiththecontrolgroupofCOPDwithrespiratoryfailureintreatmentofthetotalefficiencyishigher;P<0.05;theinterventiongroupcomparedwiththecontrolgroupofdyspnea,cough,fever;pulmonaryralesdisappearedtimeshorter;P<
6、0.05;twogroupsbeforetreatmentofCreactionprotein,oxygenpartialpressureofoxygen,twocarbonpartialpressure,FVCissimilartothatofP>0.05;2weeksofmedicationinterventiongroupcomparedwiththecontrolgroupofCreactiveprotein,PO2,pCO2,FVCimprovedmoresignificantly,P<0.05.Conclusi
7、on:thecurativeeffectofmoxifloxacininhalationtherapyinpatientswithchronicobstructivepulmonarydiseasewithrespiratoryfailureiseffective,itcaneffectivelyimprovetheclinicalsymptoms,improvelungfunction,reduceinflammation,improvethebloodgasanalysisindex,isworthyofpromotion.【ke
8、yword]moxifloxacin;inhalation;patientswithCOPDcomplicatedwithrespiratoryfailure;salbutamol;inflammation【中图分类号】
