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1、盐酸米诺环素软膏治疗慢性牙周炎的临床效果［摘要］目的探讨盐酸米诺环索软膏在慢性牙周炎治疗中的临床效果。方法收集2013年3月〜2015年2月于我科门诊就诊30例慢性牙周炎患者，每人4颗牙共120颗患牙，分为治疗组和对照组，每组60颗患牙，治疗组用盐酸米诺环索软膏治疗，对照组用碘甘油治疗，连续应用4周。比较两组治疗1、4周后牙龈指数(GI)、探诊出血(B0P)比例、探诊深度(PD)、附着丧失(AL)及临床疗效。结果治疗组1、4周GI、BOP比例、卩D与相同时间对照组比较，差异有统计学意义(P0.05
2、)o治疗组总有效率明显高于对照组，差异有统计学意义(P〈0・05)。结论盐酸米诺环索软膏治疗慢性牙周炎疗效确切，可有效降低GI、BOP比例、PD,提高临床疗效，作用明显优于碘甘油，可在临床推广应用。［关键词］分周炎；盐酸米诺环素；碘甘油［中图分类号］R781.4［文献标识码］A［文章编号］1674-4721(2015)09(b)-0094-03Clinicaleffectofminocyclinehydrochlorideointmentinthetreatmentofchronicperiodo
3、ntitisNANXiao-siCHENZhou-huanYANGYaDepartmentofStomatology,MaternalandChildHealthHospitalinLonggangDistrictofShenzhenCity,Shenzhen518172,China[Abstract]ObjectiveToexploretheclinicaleffectofminocyclinehydrochiorideointmentinthetreatmentofchronicperiodo
4、ntitis・MethodsFromMarch2013toFebruary2015,30patients(4Leechfromeachperson)withchronicperiodontitisvisitedouroutputientclinicwereselected.Therewere120involvedteethwhichwereevenlydividedintotreatmentgroupandcontrolgroup.Inthetreatmentgroup,minocyclinehy
5、drochlorideointmentwasprovided,whileinthecontrolgroup,iodineglycerinwasapplied・Thecoursesoftreatmentlasted4weeks.Thegingivalindex(GI),bleedingonprobing(BOP)ratio,probingdepth(卩D),attachmentloss(AL),clinicalefficacyafteroneandfourweekstreatmentwerecomp
6、aredbetweentwogroupsrespectively.ResultsAfteroneandfourweeks,GI,BOPratio,andPDintreatmentgroupwascomparedwiththatincontrolgroupatthesametimerespectively,withstatisticaldifferences(P0.05).Thetotaleffectiverateintreatmentgroupwasmuchhigherincomparisonwi
7、ththatincontrolgroup,withstatisticaldifference(P<0.05)•ConclusionMinocyclinehydrochlorideointmentiseffectiveontreatingchronicperiodontitis,whichcaneffectivelyreducetheGI,BOPratio,andPD,andimprovetheclinicalefficacy.Ttseffectissuperiortothatbyiodinegly
8、cerin,andcanbepromotedinclinicalpractice.[Keywords]Periodontitis；Minocyclinehydrochloride；Iodineglycerin分周炎是临床上常见的一类口腔疾病，是一种由龈沟内或牙颈部的菌斑微生物引起的慢性炎症，常发病于>35岁的人群［1］。牙周炎的早期患者多无明显症状，只有继发性牙龈出血或口臭等表现，但随着炎症的进一步扩展，会表现为炎症且有才周袋形成等，如不给予及时有效治疗或治疗效果不佳最终会导致牙齿
