[精品][经典]罗呱卡因硬膜外阻滞后异丙酚靶控输注麻醉的临床观察.doc

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1、[经典]罗呱卡因硬膜外阻滞后异丙酚靶控输注麻醉的临床观察罗呱卡因硬膜外阻滞后异丙酚靶控输注麻醉的临床观察【摘耍】目的通过脑电双频指数的监测，评价罗呱卡因硬膜外用药后对异丙酚靶控输注(TCI)时麻醉剂量和质量的影响。方法60例接受上腹部手术患者随机分为硬膜外罗呱卡因组(GR)和单纯异丙酚组(PR)二组。GR组硬膜外给药20min后,二组TCI输注异丙酚致意识消失,记录所需时间，继续全麻诱导观察插管反应。所有患者同时监测心电图(ECG),血压(MP),及脑电双频指数(BTS)并记录异丙酚的效应室浓度(

2、Ce)及用量。结果患者意识消失所需时间及异丙酚的效应室浓度、用量GR组与PR组有统计学显著差异。GR组MAP在硬膜外用药15min、意识消失时、插管后1min,与PR组相比较有显著性差异。结论罗呱卡因硬膜外阻滞可减少异丙酚靶控输注(TCT)时镇静催眠的用量，提高麻醉质量,并缩短意识消失所需的时间，并II有助于血流动力学的平稳，减轻插管反应。【关键词】罗呱卡因;二异丙酚;靶控输注Clinicalstudyoftrachealintubationgeneralanaesthesiawithtarget

3、controlledinfusionofpropofolafterepiduralropivaeaineblockYANGXing,HUANGMan,WANGYuanSheng.DepartmentofAnesthesia,JiangmenCentralHospital,Jiangmen529070,China[Abstract]ObjectiveToevaluatetheeffectoftrachealintubationgeneralanaesthesiawithtargetcontrolle

4、dinfusionofpropofolafterepiduralropivaeaineblock.MethodsSixtyASAT~TTpatientsscheduledforupperabdominalsurgerywererandomlyassignedintotwogroups:ropivaeainegroup,(groupGR,n=30)andpropofolalonegroup,(groupPR,n=30)・Twentyminutesafterepidurallocalanestheti

5、csadministration,apropofoltarget-controlledinfusionwasstarteduntiloneminuteaftertrachealintubation.Theconsumedtimeofpatientslosingconsciousness,thetargetconcentrationandtheconsumedamountofpropofol,BISandMAPwereallrecordedinfixedtime・ResultsTheconsumed

6、timeoflosingconseiousness,thetargetconeentrationandtheconsumedamountofpropofolandMAPwereallstatisticallysignificantdifferencebetweentheGRgroupandPRgroup・GRgroupofMAPintheepiduralmedication20minutes,consciousnessdisappears,1minuteafterintubation,compar

7、edwiththePRgroupweresignificantlydifferent・ConelusionEpiduralropivaeaineblockcanenhancethesedativeandhypnoticeffectofpropofoltarget-control1edinfusion,andepiduralropivaeaineblockcanimprovethequalityofanesthesia,Andcontributetothesmoothhemoclynamic,red

8、ucetheintubationresponse・［Keywords】Ropivaeaine;Propofol;Target-controlledinfusion作者单位：529070r东省江门市中心医院麻醉科有研究表明［1］利多卡因硬膜外给药具有强化全身麻醉药的镇静催眠作用，罗呱卡因是否存在相似的效应，目前尚未有相关的报道。本研究拟通过脑电双频指数(BIS)的监测，评价罗呱卡因硬膜外用药后对异内酚靶控输注(TCI)时麻醉剂量和质量的影响。1资料与方法1.1一般资料病例选择60例胆