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《58例原发性胆囊癌的临床诊治分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、第38卷黑龙江医学Vol_38.No.12014年第1期HEILONGJIANGMEDICALJOURNALJan.20147558例原发性胆囊癌的临床诊治分析杨志伟,朱大勇,陈杨,毛晓光(黑龙江省医院普外二科,黑龙江哈尔滨150036)摘要:目的探讨原发性胆囊癌的临床诊断,手术方式选择及预后。方法对我院2005—06~2012—06间收治的58例原发性胆囊癌患者的临床资料进行回顾性分析。结果术前彩超检查诊断符合率为79.3%(46/58);术前CT检查诊断符合率为87.2%(34/39);术前MRI和MRCP检查诊断符合率为77.8%;血清CA19—9及CEA阳性率分别为
2、71.8%(28/39)和61.5%(24/39)。根据TNM分期标准,本组I期3例,Ⅱ期9例,Ⅲ期l7例,Ⅳ期29例。58例患者均行手术治疗,18例行单纯胆囊切除术,其中3例I期患者获长期生存。18例行根治性切除术,根治性切除率为31%。58例病人中有45例获得随访,随访率为77.6%。其中随访的6例Ⅱ期患者及3例Ⅲ期患者术后生存期超过3年;3例Ⅱ期患者术后生存期超过5年;3例Ⅳ期患者术后分别生存16个月、20个月、21个月。结论术前影像学的联合检查可提高诊断的准确率,早期诊断和根治性手术是提高胆囊癌患者生存率的有效方法。关键词:胆囊肿瘤;诊断;手术治疗;预后doi:10
3、.3969/j.issn.1004—5775.2014.O1.043学科分类代码:320.6740中图分类号:R735.8文献标识码:B58ClinicalDiagnosisandTreatmentCasesofPrimaryGallbladderCarcinoma/YANGZhi—wei,ZHUDa—yong,CHENYang,//(TheSecondDepartmentofGeneralSurgery,HeilongjiangProvincialHospital,Harbin150036,CHINA)Abstract:0bjectiveToexploretheclini
4、caldiagnosis,surgicaloptionsandprognosisofprimarycarcinomaofgallbladder(PCG).MethodsAretrospectiveanalysiswasperformedfor58casesofprimarycarcinomaofgallbladder,whoreceivedtreatmentfromJune,2005toJune,2012inHeilongjiangProvincialHospita1.ResultsThepreoperativelocalizationaccuracyofColorDopp
5、lerultrasoundandcompu—tedtomography(CT)was79.3%(46/58)and87.2%(34/39),thepreoperativelocalizationaccuracyofMagneticResonanceImaging(MRI)andMagneticResonanceCholangiopancreatography(MRCP)was77.8%,andpositiverateofselalmCA19—9andCEAwas71.8%(28/39)and61.5%(24/39)respectively.InaccordancewithT
6、NMstagingcriteria,therewere3casesinIstage,9casesinIIstage,17casesinIIIstage,29casesinIVstage.All58patientsunderwentoperationtreatment:18patientsperformedcholecystectomyalone,anda-mongthesepatients3withIstageobtainedlongtermsurviva1.18casesunderwentradicalexcision,andtherateofradicalexcisio
7、nwas3l%.45ofthe58patientshavebeenfollowed—up.andfollow—upratewas77.6%.6patientswithIstageand3patientswithIIIstagereceivedoperationsurvivedover3years.3patientswithIIstagepostoperativesurvivaltimeexceeded5years.3caseswithIVstageper—formedextendedradicalgallbladd
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