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时间:2020-04-16
《多频生物电阻抗法评价血液透析患者体液分布.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、血液净化2o09年7月第8卷第7·375··论著·多频生物电阻抗法评价血液透析患者体液分布孙芳周亦伦刘婧马丽洁韩彬沈洋崔太根【摘要】目的利用多频生物电阻抗测量法了解维持性血液透析(HD)患者体液分布情况。方法选择透析龄大于3个月的维持性HD患者ll9名,应用多频生物电阻抗频谱分析法分别于透析前、后测定细胞外液(ECw)、细胞内液(ICw),并分别计算占体重的百分比(ECW%、ICw%)。选择性别、年龄和体重相匹配个体82例作为正常对照。结果男性和女性维持性HD患者ECw%较同性别正常对照组明显增高(男尸<0.Ol,女尸2、Cw%与同性别正常对照组无显著性差异(尸>0.O5),且透析前、后无明显变化;男女患者ECw/Icw比值透析前均显著高于同性别正常对照组(尸<0.O1),透析后虽较透析前显著降低(尸<0.01),但仍高于同性别正常对照组(尸<0.O5)。HD患者透析过程Ecw下降值与实际超滤量呈显著正相关(男,=0.572,尸<0.01;女0.556,尸<0.01)。同性别透析高血压组的ECW%透析前后均高于正常血压组和正常对照组(P3、主要表现为Ecw%显著增加;②HD脱水主要来自细胞外液,对细胞内液无明显影响;⑧利用多频生物电阻抗测量透后EcW%可能是评价HD患者干体重的有效指标。【关键词】血液透析;生物电阻抗;干体重;细胞外液中图分类号:R18.16文献标识码:AAssessment0ffIlliddistributioninpatientsOnmaintenancehemOdiaIysisbybiO-impedancespecn哪n铷A柚.!『ssUNFcmg.ZHoUYi-llln,LIUJing,MALi-j记HANBin,SHENYang,CUI1.ai—gen.DepnrtmemⅣ印7zm)4、】,Pm9,lgH唧f‘CcfZc己fvP瑚fBPgJoDD20,懈Correspondtngnumor:CUI1i—genEmnil:cMitnigen@yn}loo.com【Abstract】objec6veToeva1uatetl1enuiddis砸buti0ninpaIjents0刀majnte盯allcehemodialysisbyt量lewh0le_bodybio-impedaJ1cespecⅡloscopy.MethodsAtotal0fll9patientswitllstablehemodialysisf0rIn0reman3monmswere啪lledin5、Ⅱlisstudy.Pre-al1dpost_dialysisinn。ellu1arwater(ICW)andextracellularwater(EC、v)weremeasuredbywhoIe-body咖lti—frequencyb唧edancespec仃oscopy(B0dys龇UK),aIlds劬一d删zedbybodyweightt0produceICw%a11dECw%.Eighty-onomlalindividua1sof眦nchedsex,agea11dbodyweightwereusedascon仃ols.ReslIltsPatientsonmainten6、anceheIIl0dialysishadsignificantlyhigherECW%aIldBCW仃CW瑚ocorIlparedwiⅡlno加alconⅡols(尸<0.01).ECW%aJ1dECW/ICWmtiodecreasedsignmcaJltlyafterhemodialysis,butweresm1highertllanmoseofcon臼ols.Byconrast,pre—aIldpost_dialysisICW%valuesinHDpatientsweresimi1artothOseofcontr0ls.LowerECWafterdialysiswas7、pOsitivelycon.elatedwimul的flltrationvoluIIle(.572,P
2、Cw%与同性别正常对照组无显著性差异(尸>0.O5),且透析前、后无明显变化;男女患者ECw/Icw比值透析前均显著高于同性别正常对照组(尸<0.O1),透析后虽较透析前显著降低(尸<0.01),但仍高于同性别正常对照组(尸<0.O5)。HD患者透析过程Ecw下降值与实际超滤量呈显著正相关(男,=0.572,尸<0.01;女0.556,尸<0.01)。同性别透析高血压组的ECW%透析前后均高于正常血压组和正常对照组(P3、主要表现为Ecw%显著增加;②HD脱水主要来自细胞外液,对细胞内液无明显影响;⑧利用多频生物电阻抗测量透后EcW%可能是评价HD患者干体重的有效指标。【关键词】血液透析;生物电阻抗;干体重;细胞外液中图分类号:R18.16文献标识码:AAssessment0ffIlliddistributioninpatientsOnmaintenancehemOdiaIysisbybiO-impedancespecn哪n铷A柚.!『ssUNFcmg.ZHoUYi-llln,LIUJing,MALi-j记HANBin,SHENYang,CUI1.ai—gen.DepnrtmemⅣ印7zm)4、】,Pm9,lgH唧f‘CcfZc己fvP瑚fBPgJoDD20,懈Correspondtngnumor:CUI1i—genEmnil:cMitnigen@yn}loo.com【Abstract】objec6veToeva1uatetl1enuiddis砸buti0ninpaIjents0刀majnte盯allcehemodialysisbyt量lewh0le_bodybio-impedaJ1cespecⅡloscopy.MethodsAtotal0fll9patientswitllstablehemodialysisf0rIn0reman3monmswere啪lledin5、Ⅱlisstudy.Pre-al1dpost_dialysisinn。ellu1arwater(ICW)andextracellularwater(EC、v)weremeasuredbywhoIe-body咖lti—frequencyb唧edancespec仃oscopy(B0dys龇UK),aIlds劬一d删zedbybodyweightt0produceICw%a11dECw%.Eighty-onomlalindividua1sof眦nchedsex,agea11dbodyweightwereusedascon仃ols.ReslIltsPatientsonmainten6、anceheIIl0dialysishadsignificantlyhigherECW%aIldBCW仃CW瑚ocorIlparedwiⅡlno加alconⅡols(尸<0.01).ECW%aJ1dECW/ICWmtiodecreasedsignmcaJltlyafterhemodialysis,butweresm1highertllanmoseofcon臼ols.Byconrast,pre—aIldpost_dialysisICW%valuesinHDpatientsweresimi1artothOseofcontr0ls.LowerECWafterdialysiswas7、pOsitivelycon.elatedwimul的flltrationvoluIIle(.572,P
3、主要表现为Ecw%显著增加;②HD脱水主要来自细胞外液,对细胞内液无明显影响;⑧利用多频生物电阻抗测量透后EcW%可能是评价HD患者干体重的有效指标。【关键词】血液透析;生物电阻抗;干体重;细胞外液中图分类号:R18.16文献标识码:AAssessment0ffIlliddistributioninpatientsOnmaintenancehemOdiaIysisbybiO-impedancespecn哪n铷A柚.!『ssUNFcmg.ZHoUYi-llln,LIUJing,MALi-j记HANBin,SHENYang,CUI1.ai—gen.DepnrtmemⅣ印7zm)
4、】,Pm9,lgH唧f‘CcfZc己fvP瑚fBPgJoDD20,懈Correspondtngnumor:CUI1i—genEmnil:cMitnigen@yn}loo.com【Abstract】objec6veToeva1uatetl1enuiddis砸buti0ninpaIjents0刀majnte盯allcehemodialysisbyt量lewh0le_bodybio-impedaJ1cespecⅡloscopy.MethodsAtotal0fll9patientswitllstablehemodialysisf0rIn0reman3monmswere啪lledin
5、Ⅱlisstudy.Pre-al1dpost_dialysisinn。ellu1arwater(ICW)andextracellularwater(EC、v)weremeasuredbywhoIe-body咖lti—frequencyb唧edancespec仃oscopy(B0dys龇UK),aIlds劬一d删zedbybodyweightt0produceICw%a11dECw%.Eighty-onomlalindividua1sof眦nchedsex,agea11dbodyweightwereusedascon仃ols.ReslIltsPatientsonmainten
6、anceheIIl0dialysishadsignificantlyhigherECW%aIldBCW仃CW瑚ocorIlparedwiⅡlno加alconⅡols(尸<0.01).ECW%aJ1dECW/ICWmtiodecreasedsignmcaJltlyafterhemodialysis,butweresm1highertllanmoseofcon臼ols.Byconrast,pre—aIldpost_dialysisICW%valuesinHDpatientsweresimi1artothOseofcontr0ls.LowerECWafterdialysiswas
7、pOsitivelycon.elatedwimul的flltrationvoluIIle(.572,P
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