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1、甘草锌颗粒联合硼酸溶液局部外涂治疗轻中度［摘要］目的：观察甘草锌颗粒口服联合硼酸溶液局部外涂治疗轻中度寻常性座疮的疗效。方法：将109例轻中度（I-III级）寻常性痙疮患者随机分为三组：A组（治疗组）：给予甘草锌颗粒口服联合3%硼酸溶液外涂;B组（B对照组）：给予甘草锌颗粒口服；C组（C对照组）：给予3%硼酸溶液外涂。三组疗程均为6周，疗程结束后根据皮损数目减少及患者症状的改善情况进行疗效评估。结果：A、B、C三组痊愈分别为12例（32.4%）、3例（13.9%）、4例（12.5%）,三组总冇效率分别为81.1%、3&9%、40.7%,三组总有效率比较
2、差别具有统计学意义（P0.05）o结论：甘草锌颗粒口服联合硼酸溶液局部外涂治疗轻中度寻常性座疮疗效满意，不良反应少，方法简便，值得推广。［关键词］3%硼酸溶液；寻常性座疮；甘草锌颗粒；治疗［中图分类号1R758.73+3［文献标识码］A［文章编号:1008-6455（2014）09-0739-04ObservationonclinicaleffectsofcombinationtherapyofLicorzincgranulesandboricacidsolutioninthetreatmentofacnevulgarisZHAOZhi-guo,XUS
3、heng-jing,ZHANGCai-ping,ZHANGYu,MAChao-dong,YTNGXue-feng,DINGKe-yun(DepartmentofDermatology,TheAffiliatedofPeople，sHospitalofJiangsuUniversity,zhenjiang212002,Jiangsu,China)Abstract:ObjectiveToexploretheclinicalefficacyandsafetyofcombinationtherapyofLicorzincgranulesandboricacid
4、solutioninthetreatmentofacnevulgaris.Methods109caseswithacnevulgaris(T~IIIgrade)wererandomlyseiectedanddividedintothreegroups:combinationgroup(Agroup),controlBgroupandcontrolCgroup.Agroupweretreatedwithcombinedlicorzincgranuleswith3%boricacidsolution,whileBgroupreceivedtreatment
5、ofonlyorallicorzincgranulesandCgroupreceivedtreatmentofonly3%boricacidsolution.Eachgroupswere6weeksoftreatmentexternally.skinchangesinlesionswererecordedandadversereactionswereobserved,theefficacywasassessmentedbasedonreducingthenumberofskinlesionsandthepatient'ssymptomsscoretoi
6、mproveaftertheendoftreatment.ResultsA>B>Cthreegroupswerecured12cases(32.4%),3cases(13.9%),4cases(12・5%),andthetotalresponseratesofthethreegroupswere81.l%(30cases),38.9%(14cases),40.7%(13cases)respectively,thereweresignificantdifferencebetweenthethreegroups(P0.05).Sideeffectswere
7、observedincontrolgroupandcombinationgroup,minorsideeffectsdisappearedinthreegroupsaftertreatmentswereover.ConclusionCombinationtherapyoflicorzincgrarmlesandboricacidsolutionshowspositiveeffectinthetreatmentofacnevulgaris,highcurerate,minorsideeffectsandmethodissimpleandworthprom
8、oting.Keywords:3%boricacidsolution;acnevulgaris
