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《孕期及新生儿脐带血铅影响因素的相关性研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、184ChineseJournalofWomanandChildHealthResearch,2010,Vo1.21No.2孕期及新生儿脐带血铅影响因素的相关性研究严应元,刘建安,高小红,洪琦,郭华,潘丽明(1.广东省深圳市宝安区妇幼保健院,广东深圳518133;2.中山大学公共卫生学院妇幼卫生系,广东广州513344;3.广州市天河区妇幼保健院儿科,广东广州513344)[摘要]目的探讨新生儿脐带血铅与其母体血铅等元素的相关性及其影响因素。方法抽取280例外来劳务孕妇为研究对象,采用石墨炉原子吸收光谱法,测其孕早、
2、中、晚期、分娩时血铅、钙、锌、铁、铜和锰元素水平及其新生几脐带血铅水平,并对产妇进行问卷调查。结果280例新生儿脐血铅范围为3—151g/L,血铅水平为38.6±19.51~g/L,几何均值35.9±2.8p,g/L,新生儿脐血铅≥lO0~g/L者25例,占8.9%,新生儿脐血铅水平与母亲孕早、中、晚期及分娩时血铅水平显著正相关(r=0.351、0.328、0.639、0.812,均P<0.05);孕各期血铅均与对应期的血钙、血铁显著负相关;职业铅接触、邻近交通干线是危险因素,喝牛奶习惯为保护因素。结论新生儿血铅水平
3、与母亲血铅、环境因素和饮食习惯有关;防控新生儿铅毒损害,应采取职业保护、环境改善、营养干预等多方位进行。[关键词]血铅;影响因素;妊娠;新生儿doi:10.3969/j.issn.1673—5293.2010.02.020[中图分类号]R714;R135.11[文献标识码]A[文章编号]1673—5293(2010)02—0184—03AcorrelationstudyonunlbilicalandmaternalbloodleadlevelsandinfluencingfactorsYANYing—yuan。LIU
4、Jian.an,GAOXiao.hong,HONG0i,GUOHua,PANLi.ruingJ(1.Bao’an腑trictMaternalandC谢HealthHospitalofShenzhenCity,GuangdongShenzhen518133,Ch/na:2.FacutryofMaternalandCHealthandHygiene.SchoolofPublicHealthofZhongshanUniversity.GuangdongGuangzhou51334,China;3.DepartmentofP
5、ediatrics,TianheDistrictMaternalandChildHealthHospitalofGuangzhouCity,GnangdongGnangziwu51334,Ch/na){Abstract1ObjectiveToinvestigatecorrelationbetweenleadlevelinumbilicalcordoftheneonateandthatinmaternalserumanditsinfluencingfactors.soastoprovidebasisfortakingp
6、reventivemeasures.Methods280extrinsicpregnantwomenwerecollectedasstudysubjects.Byusinggraphiteatomicabsorptionspectrophotometer,serumlevelsofPb,Ca,zn,Fe,CuandMnofpregnantwomenindifferenttrimestersofpregnancyandatparturitionandleadlevelinumbilicalcordoftheneonat
7、eweredetected.Inaddition.theextrinsicpregnantwomenselectedreceivedquestionnaireinvestigation.Corelation.stepwiseregressionanalysisandTtestwereconductedinstatisticanalysis.ResultsTheumbilicalleadlevelof280neonateswasranged3~151“Landtheirserumleadlevelwas38.6±19.
8、5g/Landthegeometricalmeanvaluewas35.9±2.8p~g/L.25neonateshadaleadlevelinumbilicalcord≥100kt~L,accountingfor8.9%.Thereweresignificantpositivecorrelationbetweenserumleadlevelo
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