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1、第29卷第2期中华中医药学刊Vo.l29No.22011年2月CHINESEARCHIVESOFTRADITIONALCHINESEMEDICINEFeb.2011中医辨证联合化疗治疗急性白血病临床观察陈育生(新昌县人民医院血液科,浙江新昌312500)摘要:目的:观察中医辨证联合化疗治疗急性白血病临床疗效,探讨中医药治疗白血病的优越性。方法:采用中医辨证分期治疗白血病,诱导缓解期以清热解毒化瘀为主,采用自拟的扶正抗癌汤;巩固治疗期以扶正益气养阴为主,采用自拟的扶正生血汤治疗。并配合常规化疗治疗急性白血病,同时设单纯西药化疗组为对照。结果:治疗组60例达CR45例,完
2、全缓解率达75.0%,总有效率达83.3%,明显高于对照组(P<0.05);缓解所需平均时间为19.4天,较对照组明显缩短(P<0.05);毒副反应明显减少(P<0.05),且毒副反应症状较轻;其复发率为44.4%,明显低于对照组(P<0.05),而其生存质量优良者占73.3%,明显高于对照组(P<0.05)。结论:采用中医辨证联合化疗治疗急性白血病较单纯化疗明显优越,值得推广应用。关键词:中医辨证;化疗;白血病;临床观察中图分类号:R733.7文献标识码:B文章编号:1673-7717(2011)02-0440-03TraditionalChineseMedicin
3、eCombinedwithChemotherapyintheTreatmentofAcuteLeukemiaClinicalObservationCHENYu-Sheng(ZheJiangXinChangPeopieHospito,lXinchang312500,Zhejiang,China)Abstrac:tObjective:Toobservethecurativechemotherapyforacuteleukemiainclinicalefficacy,ofthesuperiorityofChinesemedicinetreatmentofleukemia.M
4、ethods:StagesTCMtreatmentofleukemia,remissioninductiontoheatJiedu-huayumainlypreparedbyself-rightingcancersoup;consolidationtreatmentperiodtorightingYiqiyangyinmainlypre-paredbyself-rightingofBloodDecoction.Andcombinedwithconventionalchemotherapyinthetreatmentofacuteleu-kemia,alsobasedm
5、edicinewithchemotherapyaloneasthecontrolgroup.Results:60patientsreachedCR45cases,completeremissionratewas75.0%,totaleffectiveratewas83.3%,significantlyhigher(P<0.05);Theaveragetimetoremissionwas19.4days,significantlyshorterthanthecontrolgroup(P<0.05);toxicitydecreasedsignificantly(P<0.0
6、5),andmildsideeffects;therecurrenceratewas44.4%,significantlylowerthanthecontrolgroup(P<0.05),whileitsexcellentqualityoflifeaccountedfor73.3%,significantlyhigher(P<0.05).Conclusion:TCMcombinedwithchemotherapyinthetreatmentofacuteleukemiaissignificantlybetterthanchemotherapyalone,shouldb
7、ewidelyap-plied.Keywords:TCM;chemotherapy;leukemia;clinicalobservation急性白血病(acuteleukemia,AL)作为造血系统常见的应,如过度的骨髓抑制;消化道症状以及心、肝、肾功能的损一种恶性肿瘤随着人们生活环境的改变其发病率越来越害等。根据我们的临床实践认为,中医配合化疗治疗急性高。本病病情重、进展快、死亡率高。病理特征是骨髓及其白血病比单纯西医或中医药治疗有明显的优势,其主要表[1]他组织中出现某一类型幼稚白细胞的广泛异常增生;增生现在减少化疗副作用的发生,提高临床疗效。为
