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《系统生物学综述（A review of systems biology ）.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、系统生物学综述doc(Areviewofsystemsbiologydoc)Systemsbiology:theintegrationofvariousomicsinformationandmethodsName:WangYufengstudentnumber:061023050IntwentiethCentury,biologyexperieneedaprocessfrommacroscopictomicroscopic,andgraduallydecomposedandrefinedintovariousmoleculesandfunctionsoforganismsbythede
2、scriptionofmorphologyandphenotype・Geneengineeringtechnologyemergedin70sandexpandedgreatlyacceleratedthedevelopmentofmolecularbiology;thehumangenomeprojectstartedin90sisthefirstbigsciencehistoryoflifescience,begantoexplorethecomprehensiveandsystematicresearchonthebiology;2003hascompletedthesequen
3、cingofhumangenomeandthemodelorganism,thefirstdiscoveredthecodeoflife・Thehumangenomeprojectandthesubsequentdevelopmentofvariousomicstechnologieshavebroughtbiologyintotheeraofsystematicscienee.Systemsbiologyisinthecell,tissue,variousmolecularstructureandfunctionoforganandthewholeorganismatdifferen
4、tlevelsandtheirinteractions,andthecomputationalbiologytoquantitativelydescribeandpredictbiologicalfunction,phenotypeandbehavior.Thatistosay,systembiologyisalargesciencecharacterizedbyholisticresearch.Systemsbiologywillbebasedonthecompletegenomesequenceoflifebypasswordtotheprocessoflife,thisisagr
5、adualprocessofintegration,bytheidentificationofvariousmolecularorganismsandtheirinteractionstoapproach,network,routemapmodule,thefinalcompletionoftheentirelife.Withthehelpofthegenomeandtranscriptomesequence,functionalgenomicsandproteomicsmethods,mappingcandrawaparticularorganism,photos,photosoft
6、ranscriptionproteininteractionmaps,photosandallthephenotypictranscriptandprotein・Theintegrationoftheinformationcanhelpuseliminatethefalsepositiveandfalsenegativecausedsingleproteomicresearchmethod,functionalannotationofgeneproductsaregivenandtheirinteractionandrelationshipbetter,isconducivetothe
7、generationofbiologicalhypothesesrelatedtothe・Computationalmethodsbasedontheseintegrateddatacanmodelbiologicalprocesses・Systembiologycanberegardedastheintegrationofaomicsapproach,theintegrationofdata,thesystematizationandmode
