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1、JournalofPediatricGastroenterologyandNutrition39:115–128©August2004LippincottWilliams&Wilkins,PhiladelphiaGuidelinefortheEvaluationofCholestaticJaundiceinInfants:RecommendationsoftheNorthAmericanSocietyforPediatricGastroenterology,HepatologyandNutritionAbstractBACKGROUNDCholestati
2、cjaundice,characterizedbyelevationofse-Fortheprimarycareprovider,cholestaticjaundiceinrumconjugatedbilirubin,isanuncommonbutpoten-infancy,definedasjaundicecausedbyanelevatedcon-tiallyseriousconditionthatindicateshepatobiliarydys-jugatedbilirubin,isanuncommonbutpotentiallyseriousfu
3、nction.Earlydetectionofcholestaticjaundicebytheproblemthatindicateshepatobiliarydysfunction.Earlyprimarycareproviderandtimely,accuratediagnosisbydetectionofcholestaticjaundicebytheprimarycarethepediatricgastroenterologistareimportantforsuc-physicianandtimely,accuratediagnosisbythe
4、pediatriccessfultreatmentandafavorableprognosis.Incontrast,gastroenterologistareimportantforsuccessfultreatmentphysiologicjaundiceandbreastmilkjaundice,commonandafavorableprognosis.TheCholestasisGuidelinecausesofjaundiceinthefirstweeksoflife,arecausedbyCommitteeoftheNorthAmericanS
5、ocietyforPediatricanelevationofserumunconjugatedbilirubin.BothareGastroenterology,HepatologyandNutritionhasformu-self-limitedmaturationaldisordersobservedinmanyin-latedaclinicalpracticeguidelineforthediagnosticfantsinthefirstweeksoflife.evaluationofcholestaticjaundiceintheinfant.T
6、heCho-Cholestaticjaundiceaffectsapproximately1ineverylestasisGuidelineCommittee,consistingofaprimary2,500infants(1,2),andisthusinfrequentlyseenbymostcarepediatrician,aclinicalepidemiologist(whoalsoprovidersofmedicalcaretoinfants.However,distin-practicesprimarycarepediatrics),andfi
7、vepediatricgas-guishingjaundicecausedbycholestasisfromnonchole-troenterologists,baseditsrecommendationsonacom-staticconditionsiscriticalbecausecholestaticjaundiceisprehensiveandsystematicreviewofthemedicallitera-muchmorelikelytohaveaseriousetiologythatneedstureintegratedwithexpert
8、opinion.Consensuswaspromptdiagnos
