[精品]铝碳酸镁咀嚼片联合奥美拉唑治疗成人活动期胃溃疡的效果.doc

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1、铝碳酸镁咀嚼片联合奥美拉呼治疗成人活动期胃溃疡的效果铝碳酸镁咀嚼片联合奥美拉哩治疗成人活动期胃溃疡的效果［摘耍］目的探讨铝碳酸镁咀嚼片联合奥美拉畔治疗成人活动期胃溃疡的临床效果。方法选择活动期胃溃疡成人患者120例,随机分为实验组和对照组，各60例。所有患者均给予甲硝400mg/次，3次/d,克拉霉素500mg/次，2次/d,疗程7d；对照组给予奥美拉呼胶囊20mg/次，2次/d；实验组给予奥美拉呼胶囊20mg/次，3次/d,铝碳酸镁咀嚼片1000mg/次，3次/d。治疗8周后，比较两组的溃疡面直径、溃疡愈合情况及腹痛缓解程度。结果实验组治疗后的溃疡直径为(1・52±0・12)mm,显

2、著短于对照组的(1.75±0.14)mm(P<0.01)o实验组的溃疡愈合率为75.00%,显著高于对照组的56.67%,差异有统计学意义(P〈0・05)。实验组的腹痛缓解率为95.00%,显著高于对照组的83.33%,差异有统计学意义(P<0.05)o结论铝碳酸镁咀嚼片联合奥美拉哇治疗成人活动期胃溃疡的临床效果优于单用奥美拉呼。［关键词］活动期胃溃疡；铝碳酸镁咀嚼片；奥美拉呼［屮图分类号］R573.1［文献标识码］A［文章编号］1674-4721(2014)08(b)-0103-03［Abstract］ObjectiveToinvest!gatetheclinicalefficien

3、cyofhydrotaicitechewabletabletcombinedwithomeprazoleinthetreatmentofadultwithactivegastriculcer・Methods120casesofadultpatientswithactivegastriculcerwereselectedandrandomlydividedintocontrolgroup(60cases)andexperimentalgroup(60cases)・Allthepatientsweretreatedbymetronida^ole400mg/time,3timesaday,c

4、larithromycin500mg/time,2timesaday,oneweakasacourse.Patientsincontrolgroupwereadditionallytreatedwithomeprazole20mg/time,2timesaday.Patientsinexperimentalgroupwereadditional1ytreatedwithomeprazole20mg/time,3timesadayandhydrotalcitechewabletablet1000mg/time,3timesaday.After8weekstreatment,theulce

5、rsurfacediameter,ulcerhealingsituation,abdominalpainremissionoftwogroupswascomparedrespectively.ResultsTheulcersurfacediameterinexperimentalgroupaftertreatmentwas(1.52+0.12)mm,significantlyshorterthanthatincontrolgroup[(1.75±0.14)mm](P<0.01)・Theulcerhealingrateinexperimentalgroupwas75.00%,signif

6、icantlyhigherthanthatincontrolgroup(56.67%),withstatisticaldifference(P<0.05)・Theabdominalpainreliefrateinexperimentalgroupwas95.00%,significantlyhigherthanthatincontrolgroup(83.33%),withstatisticaldifference(P<0.05)・ConclusionClinicalefficiencyofhydrotalcitechewabletabletcombinedwithomeprazolei

7、nthetreatmentofadultwithactivegastriculcerisbetterthanomeprazolealone・[Keywords]Activegastriculcer；Hydrotalcitechewabletablet；Omeprazole胃溃疡是临床上的常见病和多发病，是胃黏膜攻击因子过强或防御因子减弱所引发的消化道疾病[1-2]o传统上对于消化性溃疡的治疗主要分为根除幽门螺杆菌和抑制胃酸两个步骤[3]o奥美拉