丙戊酸钠与左乙拉西坦治疗小儿癫痫60例疗效分析.doc

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1、丙戊酸钠与左乙拉西坦治疗小儿癫痫60例疗效分析【摘要】目的：比较丙戊酸钠与左乙拉西坦治疗儿童癫痫的疗效。方法:将60例癫痫患儿完全随机分为丙戊酸钠纟R30例,左乙拉西坦纟R30例。丙戊酸钠组应用丙戊酸钠治疗;左乙拉西坦组应用左乙拉西坦治疗，观察治疗效果。结果:丙戊酸钠组30例癫痫患儿治疗后无效4例、有效20例、完全控制5例、加重1例、总有效率25例(83.4%)。左乙拉西坦组30例癫痫患儿治疗后无效3例、有效18例、完全控制6例、加重3例、总有效率24例(80%)。两组总有效率的比较差异无统计学意义

2、，即总有效率差异吴显著性。结论:丙戊酸钠和左乙拉西坦均是相对有效的小儿抗癫痫治疗药物。【关键词】丙戊酸钠;左乙拉西坦;癫痫;儿童【中图分类号】R729【文献标识码】A【文章编号】1007-8517(2010)12-009-2[AbstractJObjective:Tocomparethesodiumvalproateandlevetiracetamtreatmentofchildrenwithepilepsy.Methods:60patientswererandomlydividedintosodi

3、umvalproateinepilepticchildrencomplete30patientsinthelevetimcetamgroupof30patients.ApplicationofsodiumvalproatesodiumvalproategroupTreatment;LevetiracetamLevetiracetamtreatmentgroupwereobservedtherapeuticeffect・Results:Thevalproategroupof30childrenwith

4、epilepsytreated4cases,effectivein20cases,5casesofcompletecontrolandincreasedin1case,thetotaleffectiverateof25cases(83.4%).LevetiracetaminchiIdrenwithepilepsy,30patientsaftertreatmentand3cases,effectivein18cases,completecontrolin6patients,increasedin3ca

5、ses,totaleffectiverateof24cases(80%)・Thetotaleffectiverateofthedifferencewasnotstatisticallysignificant,differencebetweenthetotaleffectiveWusignificant.Conclusion:SodiumvalproateandlevetiracearerelativelyeffectiveantiepileptictherapyinchiIdren.【Keyword

6、s]sodiumvalproate;Levetiracetam;epileps^;children