Split face模式评价强脉冲光治疗面部光老化的疗效.doc

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1、Splitface模式评价强脉冲光治疗面部光老化的疗效Splitface模式评价强脉冲光治疗面部光老化的疗效李远宏昊严刘梅陈晶杨雪松徐媛媛陈洪铎作者单位：110001沈阳屮国医科人学附属第一医院皮肤科暨卫生部免疫皮肤病学重点验室［摘要］日的：采川Splitface模武对强脉冲光治疗面部光老化进行量化评价。方法：41名光老化受试者右侧面部给予强脉冲光治疗，左侧血部不予治疗。治疗前后医牛对双侧血部皮肤进行整体评分，测定皮肤黑素指数、红斑指数和角质层含水量。治疗结束后1个月进行患者满意度自评。结果：右血'部治疗后医生主观评分显著下降，患者满意率为90.2

2、4%；第4次及第5次治疗后黑素指数和红斑指数下降最明显，其次为第1次治疗后。治疗对旳质层含水量影响不显著。结论：强脉冲光可安全而有效地治疗血部皮肽光老化。［关键词］SplitPace；强脉冲光；光老化TheEvaluationUsingSplitFaceLiYH,WuYan,ofTreatmentofFacialPhotoagingWithIntensePulsedLightModelLiuMei,ChenJing,YangXS,XuYY,Hong-DuoCHENDepartmentofDermatology,No1HospitalofChinaM

3、edicalUniversity,Shenyang110001,China[Abstract]ObjectiveToevaluatetheefficacyofanewIPLdeviceonthetreatmentoffacialphotoagingusingsplitfacemodel.MethodsForty-onephotoagingsubjectsweretreatedwithintensepulselightontheirrightsideofface.Theleftcounterpartwasleftuntreatedascontro1.

4、Assessmentofglobalphotoagingscoreswereperformedbydoctorsbeforeandafterthetreatment.Skinmelaninindex,erythemaindex3ndsurfacewatercontentweremeasuredbeforeandaftereachtreatment.Pertients'satisfactionratewasalsoassessed4weeksafterthefinaltreatment.ResultsAfterthetreatment,theglob

5、alphotoagingscoresoftherightfaceassessedbydoctorsdecreasedsignificfinlly.Thepatients，seif-esteemedsatisfactionratereached90.24%.Thefacialmelaninindexanderythemaindexdecreasedobviouslyafterthe1sttreatment,andthemostsignificantlychangesoccurredafterthe4thandthe5thtreatment.There

6、wasnostatisticallysignificantdifferenceofsurfacewatercontentbeforeandafterthetreatment.ConclusionIntensepulselightisasafeandefficientmodalityforfacialphotoagin百.[Keywords]Splitface;photoaging;ir)tensepulsedlight1•试验日的评价强脉冲光(intensepulsedlight,IPL)对面部光老化、雀斑、黄褐斑等皮损的治疗效果。2•试验期间20

7、06年8月~2007年8月3.试验方法3.1.受试者入组%11.1.入选标准3.符合光老化诊断标准者。皮损包括：皮肤粗糙，皱纹，面色萎黄，毛细血管扩张或面部红斑，色素斑或不规则色素沉着等色素改变，毛孔粗人以及脂溢性或tl光性角化等，80%受试者合并两种或两种以上皮损。4.符合雀斑诊断标准者。5.符合黄褐斑诊断标准考。3.排除标准4..2周之内经受H光曝晒者；5..血部有炎症性或感染性皮肤疾病者；6..全身有严重皮肤疾病或系统性疾病者；7..瘢痕体质者；8..妊娠或哺乳期者；9..有光敏史者;4..1年内应川(外用或口服)维A酸类药物考；⑧1个月内应

8、用(外川或口服)糖皮质激索或抗组胺药或光敏药物者；⑨存有过高期望值或不配合治疗者知情同意试验开始之前，试验负责医生应对受试