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时间:2020-03-21
《奥曲肽保守治疗直肠癌根治术后早期炎症性肠梗阻40例.pdf》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、2014年10月5日第23卷第l9期中l司荔·临床医药·Vo1.23,No.19,October5,2014CinaarmaceuticalsClinical朋edicine奥曲肽保守治疗直肠癌根治术后早期炎症性肠梗阻40例金宗英,钟旗,成川华(泸州医学院附属中医院肛肠科,四川泸州646000)摘要:目的观察奥曲肽保守治疗直肠癌术后早期炎症性肠梗阻患者的临床疗效。方法选取2013年4月至2014年4月行保守治疗的直肠癌根治术后早期炎症性肠梗阻患者80例,随机分为治疗组和对照组,各40例。对照组进行禁食禁饮
2、、持续胃肠减压、静脉营养支持、纠正酸碱平衡紊乱以及抗感染等常规治疗,治疗组在对照组治疗基础上加用奥曲肽,观察并记录两组患者的临床疗效、症状缓解状况、治疗前后胃肠减压引流量以及不良反应。结果治疗组总有效率为85.00%,明显高于对照组的55.00%(P<0.05)。治疗组患者腹痛腹胀缓解时间以及肛门排气排便时间均低于对照组,胃肠减压引流量明显比对照组少(P<0.05);两组患者不良反应主要是电解质紊乱以及白细胞异常,不良反应发生率组间比较无明显差异(P>0.05)。结论奥曲肽用于术后早期炎性肠梗阻的保守治疗
3、临床疗效好,且不良反应并无增加,值得临床推广。关键词:奥曲肽;术后早期炎症性肠梗阻;临床疗效中图分类号:R969.4;R977.6文献标识码:A文章编号:1006—4931(2014)19—0095—02EficacyofOctreotideforCOnserVatiVelyTreatingEarlyInflammatoryIleusafterRadicalOperationinColorectalCancerin40CasesfinZongying,ZhongQi,ChengChuanhua(Depar
4、tmentofAnorectology,AffiliatedHo~italofTraditionalChineseMedicine,LuzhouMedicalCollege,Luzhoa,Sichuan,China646000)Abstract:ObjectiveToobservetheclinicalefficacyofoctreotideintheconservativetreatmentofearlyinflammatoryileusaftercol—orectalcanceroperation.M
5、ethods80casesofearlyinflammatoryileusaftertheradicaloperationofcolorectalcancerinourhospitalfromApril2013toApril2014wereselectedandrandomlydividedintothetreatmentgroupandthecontrolgroup,40casesineachgroup.Thecontrolgroupwasgiventheroutinetherapyoffastinga
6、ndwater—deprivation,continuousgastrointestinaldecompression,intra—venousnutritionalsuppo~,correctingacid—basebalancedisordersandanti—infection,whileonthisbasisthetreatmentgroupwasaddedwithoctreotide.Theclinicaleficacy,symptomaticalleviationcondition,drain
7、agevolumeofgastrointestinaldecompressionbeforeandaftertreatment,andadversereactionswereobservedandrecorded.ResultsThetotaleffectiveratewas85.00%inthetreatmentgroupand55.00%inthecontrolgroup,thedifferencewasstatisticallysignificant(P<0.05),therelieftimeofa
8、bdominalpainandabdominaldis—tensionandthetimeofanalexhaustanddefecationinthetreatmentgroupwereshorterthanthoseinthecontrolgroup,thedrainagevolumeofgastrointestinaldecompressioninthetreatmentgroupwassignificantlyless
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