偏头痛患者血浆内皮素及降钙素基因相关肽测定的临床意义论文.doc

《偏头痛患者血浆内皮素及降钙素基因相关肽测定的临床意义论文.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、編头痛廉考Hl嗓内廈董砂締肆肄闻轴M測定的轄耘必wm«W硕弹输卖藉•遨書ifr嚟肉咸秦心4耐血t斤。［和鮒强時和降4flXH(cjlcitormi^generelatedpeptide.CORP)含_£•探讨比弃9头柿发4醸鹅陥史为劇触琲购特就蘇.MRP〉含此探讨其在倔头M4na2w..i方法选择34例诊断明扌解衍為头拓息若，按发切时间分为发作期和缺:臓谕翔潇槊敝霸W筋R2分别测定ET及CORP含"漳用密骗硼繳删貯總虢豬翌训関a灣尉捫IA)分别测定E丁及CJ蚩東偏次純缓Er&CORP对黒组(1X0.01)：史度发觸鼎犠緘眺躺汕

2、卅亍辭粋隔了y镰酬护疗羯就嘤碱瀛縱鹼粥对劇油匕7爼呼觀有疣计学童义/•眈胭關條爵戢型•财洶阀鶴融:锻沁1):和砒期姐黑躡47,,05)ETfnCORP含■受化呈正相关.偽头痛辭郦ME者（p<0-°5'能如ferJh*aik.carpvii右■统计料涂議A°宓委漏过程山㈱斤玄头辭谧界醪试鼬触沪心0•‘小’501)和间恥期*1(FO.6047.pV0・05〉ET和CGRP含：&变化呈正相关。偏头病发作患者经西叱灵治疗后血浆CGRP水平显著下降(pVo・01结论偏头师忠者血浆ET及CGRP水平的变化可能参与了偏头病的—嚏发病过程。关

3、键词偏头痛.内皮素.降钙素基因相关肽Theclinica1thep1asmaendothefinedpeptidesignificanceofdetectionofandca1citoningenere1attientswithmigraAbstractobjeetihMeasurethasmaendothelin(ET)andcpeptide(CGRP)inpoti*11hthcdevelopmentofmigrevidenceofpreventIngthem°cMethods34patientswithmigrainewh

4、ichattainedthediagnosIicprincipleandrioi:匕headache—freeperiodwerebloodI•ofplasmaETandc;Kradioimmunoassay(RlA)method,auETandCORPwerecowithcogroupcomp'healIhy卩er$onmparediur!MmigIaIne»<

5、ResultThelevelsofH：CGRPinmigrainewereohigherthanTheclinicalsignificanceofdetectionoftheplasmaercndothclinandcalcitoningenerelatedpeptideinthanthstdurinssIi?htcksanahcadachc・『lecP*riod(p<0.05tP<0.0patientswithmigraineAbstract,.ncontccofC：GRpduac*1v41儿headache—freeper

6、iodwashObjectivenJoMeasurelhelevelsofaddhcHn(ET)andcalcilcmingcrcirelated：p©pt;dc(.CpGfU^tnipatientswith:migraineo

7、swithmigraineshichattainedthediagnosticprincipleanddividedentmMtudcpetirtd1antbhead3t7>e-frctt)periodwereid>

8、ctrolgroupcomposedof31healthypersuns.22patients^duringkmigraineMert"observedthe?ttkittipcutic加用11umeasuredthechangesinplasmacoiilt4ilofETa