不同方法治疗肺栓塞的临床疗效比较.doc

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1、不同方法治疗肺栓塞的临床疗效比较【摘要】目的探讨肺栓M(PE)的最佳治疗方案。方法我院80例经CT检査确诊为肺栓塞的患者，采用溶栓、单纯抗凝法、手术/介入取栓法治疗，根据病情正确选择治疗方案，比较并分析不同治疗方案的临床疗效。结果抗凝治疗26例，总有效率为92%,溶栓治疗39例，总有效率为87%，两组疗效比较差异有显著性(P<0.05),但病死病例比较差异无显著性；手术/介入成功率为47%,病死率为14%,与溶栓纽和抗凝纽均有显著比较差异(M0.05)o结论早期诊断、早期治疗及根据病恬采用不同的治疗措施对患者至关重要，加强抗凝治疗可明显

2、降低肺栓寒患者的死亡率，改善预后。【关键词】肺栓塞；治疗选择；疗效评价；抗凝治疗Comparisonoftheclinicalefficacyofdifferentapproachestothetreatmentofpulmonaryembolism.[Abstract]ObjectiveToexplorethebestregimenoftreatmentofpulmonaryembolism(PE)forearlydiagnosisandtreatmenttoreducepatients1painandmortality.Method

3、sEightypatientswithPEdiagnosedbyCTweretreatedwithdiftcrcntregimen:thrombolytic,anticoagulantsaloneandembolectomy.Topromptlychoosetherapeuticregimen,theresultswerecompared.ResultsOfthe26paticntstreatedwithanticoagulantsalone92%showedimprovementinCTandclinicalpresentation,

4、thepercetagewassignificantlyhigherthanthatofthethrombolyticgroupwhoserateofimprovementwas87%(P<0.05).However,therateofmortalitywerenotsignificantlydifferentbetweenthrombolyticnndanticoagulantsalone・Thesuccessrateofembolectomywas47%,butmortalityratewas14%whichwassignifica

5、ntlydifferentfromthrombolyticandanticoagulantsdlone(P<0.05).ConclusionItisimportantofearlydiagnosisandtreatmentforpatientsandchooseappropriatetherapeuticregimenduetopaticnts'condition.Mortalitycouldbereducedandprognosiscouldbeimproved・[Keywords]Pulmonaryembolism;Treatmen

6、tchoice;Evaluationoftherapeuticefficacy;Anticoagulantsalone