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1、AbstractObjective:Thestudyaimedatevaluatingtheeffectofpharmaceuticalcareinterventionsonmedicationadherenceofpatientswithprimaryhypertensiori・Methods:Aprospective,randomized,controlledtrailof60patientswascarriedout,eachpatientwasfollowedupfor3months.Med
2、icationadherencewasmeasuredbythepatients1medicationcompliancerecordcardandMMASscore・Dosingcompliance(DC)andtimingcompliance(TC)werecalculatedforeachpatient.Results:Pharmaceuticalcareofhypertensionpatientsledtoasignificantincreaseincompliancewiththeanti
3、hypertensivetherapy.ThemeanDCandTCoftheinterventiongroupwassignificantlyhigherthanthecontrolgroup.Theinterventiongroupdemonstratedahigherpercentageofpatientswithhighadherence(72.41%)at3months,whereasthecontrolgrouphardlyhadchangesinmedicationcompliance
4、・Conclusion:Patientswhoreceivedpharmaceuticalcareshowedsignificantlybettercompliancewiththeirantihypertensivemedicationthanpatientswhoreceivedonlytraditionalpatientcare.Pharmaceuticalcareprovedtobeaneffectiveinterventionthatshouldbeimplementedinhyperte
5、nsioncare.Keywords:primaryhypertension,anti-hypertensivetherapy,pharmaceuticalcare,medicationadherenceINTRODUCTIONSeveralclassesofdrugsareavailabletotreathighbloodpressure(BP)andshouldbesufficienttocontrolhypertensioninmostpatients.BPcontrol,however,is
6、achievedinonlyabout30%ofpatients.evenafterintensivetreatmentwithseveraldrugsfromdifferentclasses卩习.Noncompliancewiththeantihypertensivedrugsisoneofthemostimportantetiologicalfactorsforunsatisfactorybloodpressurecontrol囚.Numerousfactorsarcinvolvedinpoor
7、patientresponsetomultipleantihypertensiveagents,includingnon-adherencetorecommendedtherapy,asuboptimaltherapeuticregimen,druginteractions,thepresenceofsodiumorvolumeoverload,andwhite-coathypertension,aswellassecondarycausesofhypertension^41.Giventheman
8、yfactorscontributingtopoorcompliance,multifactorialinterventionsarerequired⑸.Combiningeducational,behavioralandtechnicalinterventions,pharmaceuticalcareissuchamultifactorialapproach.Theaimofpharmaceuticalcareistopromotecompliance,toprev
