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《抗幽门螺杆菌治疗对急性冠脉综合征合并幽门螺杆菌感染患者的近期疗效.doc》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、抗幽门螺杆菌治疗对急性冠脉综合征合并幽门螺杆菌感染患者的近期疗效[摘要]目的探讨抗幽门螺杆菌治疗对急性冠脉综合征合并幽门螺杆菌感染患者近期疗效的影响。方法选取我院收治的66例合并幽门螺杆菌感染的急性冠脉综合征患者,随机分为常规冠心病药物治疗的对照组(n=33)和抗幽门螺杆菌感染治疗的实验组(n二33),对照组予常规的冠心病药物治疗,实验组在常规冠心病药物治疗的基础上加用泮托拉卩坐(40mgbid)、复方铝酸祕(130mgtid)、阿莫西林(100mgbid)及克拉霉素缓释片(100mgqd)抗幽门螺杆菌治疗,疗程10d。10d后比较两组患者TG
2、、TC、LDL・C、HDL・C、C3、C4、CRP、FIB治疗前后的变化情况,并评价临床用药安全性。结果实验组与对照组患者的TG、TC、LDL-C>C3、C4、CRP、FIB水平与治疗前相比均不同程度的降低,其中实验组C3、CRP、FIB降低幅度明显大于对照组(P[关键词]幽门螺杆菌;抗幽门螺杆菌感染;急性冠脉综合征;近期疗效评价[中图分类号]R541.4[文献标识码]B[文章编号]1673-9701(2016)25-0030-03Short-termcurativeeffectsofanti-helicobacterpyloritherapy
3、onthepatientswithacutecoronarysyndromeCHENQianshengFANGYongLIWeiguoHUANGGuoyongLIGanyangCHENLilingSONGWeiCHENKaihongDepartmentofCardiology,LongyanFirstHospitalAffiliatedtoFujianMedicalUniversity,Longyan364000,China[Abstract]ObjectiveToexploretheshort-termcurativeeffectsofant
4、i-helicobacterpyloritherapyonthepatientswithacutecoronarysyndromecomplicatedwithhelicobacterpyloriinfection.Methods66patientswithacutecoronarysyndromecomplicatedwithhelicobacterpyloriinfectionwhowereadmittedtoourhospitalwereselected.Theywererandomlyassignedtothecontrolgroup(
5、n=33)whoweregivenregularmedicationforcoronaryheartdisease,andtheexperimentgroup(n二33)whoweregiventhetherapyofanti-helicobacterpyloriinfection.Thecontrolgroupwasgivenregularmedicationforcoronaryheartdisease,andtheexperimentgroupwasfurthergiventhetherapyofanti-helicobacterpylo
6、riinfectionbypantoprazole(40mgbid),compoundbismuthaluminateonC130mgtid),amoxicillin(100mgbid)andclarithromycinsustained-releasetablets(100mgqd)onthebasisoftheregularmedicationforcoronaryheartdisease.Thecourseoftreatmentwas10days・ChangesofinflammationmarkerssuchasTG,TC,LDL-C,
7、HDL-C,C3,C4,CRPandFIBbeforethetreatmentand10daysafterthetreatmentwerecomparedbetweenthetwogroupsofpatients,andthesafetyofclinicaldrugusewasevaluated.ResultsTheTC,TG,LDL-C,HDL-C,C3,C4,CRP,FIBwereloweredbothintheexperimentgroupandthecontrolgroupthenbeforetreatment,buttheconten
8、tsofC3,CRP,FIBandotherinflammationmarkersintheexperimentgroupwereallsignifi