组会文献汇报模板.ppt

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1、Preparation,Characterization,Cytotoxicity,andGenotoxicityEvaluationsofThiolated-andS‑NitrosatedSuperparamagneticIronOxideNanoparticles:ImplicationsforCancerTreatmentAmedeaB.Seabra,*,†TatianePasquoto,‡AnaCarolinaF.Ferrarini,†MarconidaCruzSantos,†PaulaS.Haddad,†andRenatadeLima§IntroductionResult

2、anddiscusionCharacterizationofThiolatedFe3O4Nanoparticles.Theresultsrevealedthatthiolatednanoparticleshavelowtoxicity,whereasS-nitrosonanoparticleswereobservedtocausecytotoxicandgenotoxiceffectsindifferentcelllines.Furthermore,themagneticpropertyoftheS-nitrosatednanoparticleswasusedasatooltogener

3、atealocalcytotoxiceffectdirectlyatthetargetsiteofapplication.S-Nitrosatednanoparticlesappeartoconstituteapotentiallypromisingagentforthetreatmentofcancerandpreventionofthemetastaticcascade;therefore,furtherstudiesarerequiredtoclearlyunderstandthecomplexandwide-rangingrolesofNOtofacilitateitsther

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