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1、甲泼尼龙联合阿奇霉素治疗小儿支原体肺炎的临床疗效［摘要］目的研究讨论甲泼尼龙联合阿奇霉素对小儿支原体患儿的安全性与临床疗效。方法在2013年10月一2015年2月来该院治疗小儿支原体的患者中随机抽取90例，将其按随机数字表法分为观察组和对照组各45例。给于对照组患儿静脉滴注药物阿奇霉素，按10mg/kg,共治疗7d；在对照组的基础上给予观察组患儿静脉滴注药物甲泼尼龙，按2mg/kg，待患儿体温恢复到正常时改为口服药物甲泼尼龙片，按1mg/kg,共治疗5do观察比较两组患儿不良反应的发生状况、临床疗效、住院时间、退热时间和
2、咳嗽的消失时间。结果研究结果表明，观察组患儿的总有效率(93.33%)显著高于对照组(82.22%)；观察组患儿的住院时间、退热时间、咳嗽的消失时间均显著短于对照组患儿，其差异具有统计学意义(P0.05)o结论甲泼尼龙联合阿奇霉素可以有效治疗小儿支原体肺炎,该两种药物合用可有效控制患儿病情，快速缓解其临床体征，且安全性高,值得临床广泛应用。［关键词］支原体肺炎；小儿；阿奇霉素［中图分类号］R4［文献标识码］A［文章编号］1674-0742(2015)12(c)-0121-03ClinicalCurativeEffecto
3、fMethylprednisoloneCombinedwithAzithromycininTreatmentofMycoplasma卩neumoniainChildrenYANGChun-yan,WANGYunDepartmentofpediatries,XuzhouCentralHospital,Xuzhou,JiangsuProvince,221000China[Abstmet]ObjectiveToresearchanddiscussthesecurityandclinicalcurativeeffectofmet
4、hylprednisolonecombinedwithazithromycinintreatmentofmycoplasmapneumoniainchildren.Methods90casesofpatientswithmycoplasmapneumoniainchi1drentreatedinourhospitalfromOctober2013toFebruary2015wereextractedandrandomlydividedintotwogroupswith45casesineach,thecontrolgro
5、upweretreatedwithintravenousinfusionofazithromycin(lOmg/kg)for7days,theobservationgroupweretreatedwithintravenousinfusionofmethylprednisolone(2mg/kg)onthebasisofthecontrolgroup,anditwasinsteadoforaladministrationofmethylprednisolonetablets(lmg/kg)for5dayswhenthec
6、hildren,sbodytemperaturereturnedtonormal,theoccurrenceofadversereactions,clinicalcurativeeffect,lengthofstay,feverreducingtimeandcoughdisappearaneetimeofthetwogroupswereobserved.ResultsTheresearchresultsshowedthatthetotaleffectiverateintheresearchgroupwasobviousl
7、yhigherthanthatinthecontrolgroup,(93.33%vs82.22%),thelengthofstay,feverreducingtimeandcoughdisappearancetimeintheobservationgroupwereobviouslyhigherthanthoseinthecontrolgroup,andthedifferenceswerestatisticallysignificant(PO.05).ConclusionMethylprednisolonecombine
8、dwithazithromycincaneffectivelytreatmycoplasmapneumoniainchildren,thecombinedusecaneffectivelycontrolthechildren'sdiseasecondition,relievetheirclinicalsignsqui
