资源描述：
《复方牛胎肝提取物治疗乙型肝炎肝硬化疗效观察.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、复方牛胎肝提取物治疗乙型肝炎肝硬化疗效观察卢敏，毛华，黄纯炽，唐银丽，张能友，席建东【摘要】H的探讨复方牛胎肝提取物治疗乙型肝炎肝硬化患者的疗效。方法将120例乙型肝炎肝硬化患者随机分为治疗组80例和对照组40例。给予治疗组复方牛胎肝联合基础护肝治疗，对照组仅予以基础护肝治疗，疗程3个刀，对比两组患者治疗前后肝功能、肝脏硬度值(LSM),以及B超检测门静脉内径、脾脏厚度、脾静脉宽度的变化。结果在3个月治疗结朿吋，治疗组患者血清TBIL为(33.0±2.07)屮nol/L、ALT为(36.40±5.86)U/L、
2、LSM为(10.78±1」5)Kpa,均较对照组显著下降[分别为(48.62±4.24)pmol/L、(52.60±7.3)U/L、(15.26±2.17)Kpa,P<0.05];治疗组血清ALB水平为(35.0±1.58)g/L,较对照组明显升高[(31±1.58)g/L,P<0.05];治疗组门静脉内径为(1.26±0.08)cm,脾脏厚度为(3・97±0.04)cm,脾静脉宽度为(0.87±0.02)cm,均较对照组显著降低[分别为(1.36±0.05)cm、(4.20±0.10)cm>(0.92±0.0
3、2)cm,P<0.05]o结论复方牛胎肝提取物可显著改善乙型肝炎肝硬化患者的肝功能，减轻肝纤维化程度。【关键词】肝硬化;乙型肝炎;复方牛胎肝提取物;疗效DOI：10.3969/j.issn.1672-5069.2015.02.011EfficacyofcompoundembryonicbovineliverextractinpatientswithhepatitisBrelatedlivercirrhosisLuMin,MaoHua,HuangChunchi,etal.DepartmentofGastroent
4、erology,ZhujiangHospitalAffiliatedtoSouthernMedicalUniversity,Guangzhou510282,GuangdongProvince,China[Abstract]ObjectiveToinvestigatetheeffectofcompoundembryonicbovineliverextractinpatientswithhepatitisBrelatedlivercirrhosis.MethodsOnehundredandtwentypatient
5、swithhepatitisBinducedlivercirrhosiswererandomlydividedintotwogroups,with80intreatmentgroupreceivingcompoundembryonicbovineliverextracttabletsatthebaseofbasicliver-protectingtreatmentand40incontrolgroupreceivingthebasicliv・er-protectingtreatmentonlyfor3month
6、s.Liverfunctiontests,liverstiffnessmeasurement(LSM)byFibrotouch,andportalveindiameters,spleenthicknessandsplenicveinwidthbeforeandaftertreatmentwerecomparedinbothgroups・ResultsAttheendof3-monthtreatment,scrumTBIL,ALT,andLSMvaluesinpatientsintreatmentgroupwer
7、e(33.0±2.07)pmol/L,(36.40±5.86)U/L，(10.78±1.15)Kpa,respectively,significantlydecreasedascomparedwiththoseinthecontrols[(48.62±4.24)pmol/L,(52.60±7.3)U/L,(15・26±2」7)Kpa,respectively,P<0.05forall];scrumALBlevelsinpatientsintreatmentgroupincreasedsignificantlyc
8、omparedwiththatincontrols[(35.0±1.58)g/Lvs.(31±1.58)g/L,P<0.05];portalveindiameters,spleenthicknessandsplenicveinwidthsremarkablydecreasedcomparedwiththoseinpatientsinthecontrolgroup[(1.26±0.08)
