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1、BY-mmboy@猪八戒威客TheClinicalPathologyAnalysisofLobularInfiltratingCarcinomaABSTRACT[Objective]:InvestigatingthedisciplinesandfeaturesofBreastLobularInfiltratingCarcinomabyanalyzingtheClinicalPathologyfeaturesoflobularinfiltratingcarcinomapatients・[MaterialandMetho
2、dolog刃：FromJan.2001toDec.200&ourhospitalhadwitnessed68casesofpeoplewhoreceivedoperationsandwerediagnosedasprotoplasmicBreastLobularInfiltratingCarcinomabyclinicalinspections.Ourstatisticsincludefeaturesofclinicalobservationandtumorpathologysuchasagedistribution
3、,menstruationsituation,tumorposition,Ultrasonography,molybdenumanodeX-rayRadiograph,TNMClassificationandimmunohistochemistry.Wealsocompareourfirst-handmaterialswiththoseofBreastLobularInfiltratingCarcinomainordertomakeadeepanalysis.[ResearchFruits]：Theagevulner
4、abletoBreastLobularInfiltratingCarcinomamainlyfallswithin40-49,29casesintotal(42.7%)；Thesecondaryagevulnerablefallswithin50-59,16cases(23.5%),amongwhichtheyoungestpatientis30yearsoldwhiletheeldestis79,50.2inaverages・Pre-menopausalwomen:39cases(57.4%),menopausal
5、women:29cases(42.6%)；Protoplasmictumorintheleftgalactophore:31cases(45.6%),thatintherightgalactophore:35cases(51.5%),inbothsides:2cases(2.9%).Inmostcases,protoplasmictumorsarealwaysintheupperouterquadrantofgalactophore,27casesintotal(45.0%).Beforeoperation,Ultr
6、asonographyshows4positivecases.WehadalsoemployedmolybdenumanodeX-rayRadiographtoinspect12patients,finding11positivecases(91.7%).AccordingtotheTNMClassificationofAJCC,theresultisasfollows:PhaseI:8cases(12.9%),PhaseII:37cases(59.7%),PhaseIIIPeases(27.4%)；Theimmun
7、ohistochemistryreportisasfollows:ER・positive55cases(87.3%),PR・positive56cases(88.9%),HER-2positive:14cases(22.2%).ThereisnonotabledifferencebetweenILCandIDCpatientsintermsofagedistribution,menstrualsituationandtumorsize(P>0.05).However,theydohavenotabledifferen
8、cesintermsofthepositiveproportionofaxillarygland,ER&PRandHER-2(P<0.05)[Conclusion]：TheagevulnerabletoILCisfrom40to49,whichisinfullaccordancewiththeintegralstructureofpathoge
