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1、自体微粒皮移植术修复深度烧伤创面的临床分析张宜澜彭代智段小冬何斌周灵李睿夫黄亚兰刘洋甘雨400038重庆,第三军医人学西南页院全军烧伤研究所,创伤、烧伤与复合伤国家重点实验室[基金项目]卫牛部卫住行业科研专项(201202002)[通信作者]彭代智,电话:(023)68754226,E-mail:dzpengpub@126.com[摘要]目的总结自体微粒皮移植术修复深度烧伤创面的临床资料,对其死亡率、早期创面愈合情况及近、远期愈合质量进行评估。方法收集我院2002年11月〜2013年8刀期间入院采用自体
2、微粒皮移植术治疗大面积深度烧伤患者214例的临床资料,分析治疗过程屮的各因素对患者预后、创而愈合情况以及近、远期愈合质量的影响。结果伤后一周内行切痂微粒皮移植能明显降低患者的死亡率。对377个部位的创面愈合率进行分析,适当的扩展比例(5:1〜10:1)具有良好的愈合率(与小于5:1比较)及愈合速率(与大于10:1比较)。对307个部位的创面近期愈后质量进行分析,发现反复破溃是微粒皮移植术后的一个普遍现象。4•在对189个部位的远期愈合质量分析,证实了瘢痕增生程度与创而一期愈合率关系密切。结论口体微粒皮移
3、植术在大面积深度烧伤患者的早期创面封闭起到关键作用,但其创面愈后还存在很多问题,如创面愈合率较低,创面愈后反复破溃以及后期瘢痕增生等问题。[关键词]深度烧伤;微粒皮;扩展比;创面愈合;瘢痕增生;ClinicalefficiencyofautologousmicroskingraftinginrepairingextensivedeepburnwoundsZhangYilan,PengDaizhi,DuanXiaodong,HeBin,ZhouLing,LiRuifu,HuangYalan,LiuYang
4、,GanYuInstituteofBurnResearch,SouthwestHospital,StateKeyLaboratoryofTrauma,BurnsandCombinedInjury,theThirdMilitaryMedicalUniversity,Chongqing40003&China[Abstract]ObjectiveTosummarizetheclinicaldataofautologousmicroskingraftinginpatientswithextensivedeepb
5、urnwounds,andevaluatetheoutcome,theprimarywoundhealingrate,andthequalityofhealedwoundsinboththeshortandlongterms.MethodsAutologousmicroskingraftingwasperformedin214patientswithsevereburnsduringtheperiodofNovember2002〜August2013atourcente匸Theirclinicaldat
6、a,includingdemographicinformation,theoutcome,skingraftingoperationparameters,woundhealingindexesaswellasthedegreeofscarhyperplasia,wereallcollectedandcategorized.Therelationshipbetweenthemortalityandthepostburndaysofoperationwasanalyzed.Theinteractionsam
7、ongskingrafting,woundhealingandscarringwerealsoinvestigated.ResultsThepatientsunderwentaggressiveescharexcisionsandautologousmicroskingraftingwithinsevendayspostburnsignificantlyreducedthemortality.Intermsofexpansionratiobetweenrecipient-sitetodonor-site
8、surfaceareaforatotalof377skingraftingsites,theratiorangingfrom5:1to10:1hadahigherprimarywoundhealingratethanthatoflessthan5:1,andabetterwoundhealingspeedthanthatofmorethan10:1.Theshorttermqualityofhealedwoundsin307skingraf