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1、子宫动脉栓塞治疗子宫腺肌症长期随访探究【摘要】目的观察子宫腺肌症患者介入治疗后的长期效果。方法对39例子宫腺肌症患者进行聚乙烯醇微粒和明胶海绵碎粒双侧子宫动脉栓塞。术后随访2年,观察月经及子宫体积等变化情况。结果全部患者行双侧子宫动脉栓塞成功。31例术后3月痛经完全消失,8例痛经减轻,较介入治疗前患者疼痛评分明显降低;所有患者月经量平均减少42%(P<0.01);超声见子宫病灶消失34例(87.2%),明显缩小5例(12.8%)o随访2年,痊愈31例(79.5%),好转8例(20.5%)。随访期间2例于术后9、11个月因人工流产后复
2、发。1例术后10个月出现痛经加重,腹腔镜手术证实为盆腔炎性包块,术后随访至12个月,无异常。复发率为7.7%;妊娠8例(20.5%)o结论通过2年的随访观察,介入治疗子宫腺肌病在保留了子宫和生育能力的同时还具有创伤小、症状缓解迅速,不易复发等优点。【关键词】子宫腺肌症;介入治疗;随访Uterinearteryembolizationforadenomyosislong-termfollow-upstudyLIANGGui-ling,YANHua,ZHENGZhan-chuan,XULi-ping,MIJian-feng,SUXiao
3、-rong.TheSecondPeople,sHospitalofQinzhou,Qinzhou535000,China【Abstract】ObjectiveToinvestigatetheinvolvementofadenomyosisinpatientswithlong-termeffectsaftertreatment・Methods39casesofuterineadenomyosisinpatientswithalcoholandgelatinspongeparticlescrushedbilateraluterinear
4、teryembolizatiori.Werefollowedupfor2years,observationandothermenstrualanduterinevolumechanges・ResuItsAllpatientssuccessfullyunderwentbilateraluterinearteryembolization.31casesofdysmenorrheadisappeared3monthsafter,and8toreducedysmenorrhea,comparedwithbeforeinterventioni
5、npatientswithpainscoresweresignificantlylower;averagereductionofmenstrualflowinallpatients42%(P<0.01);seeingtheuterusunderultrasoundlesionsdisappearedin34patients(87.2%),significantlyreducedin5cases(12.8%)・2-yearfoilow~up,cured31patients(79.5%),improvedin8cases(20.5%).
6、2casesduringthemonthsaftertheoperationfor9,11recurrenceafterabortion.1casere-emergedinOctoberafterincreasingdysmenorrhea,laparoscopicsurgeryconfirmedpelvicinflammatorymass,patientswerefollowedupinDecemberhasbeennoexceptiori.Recurrenceratewas7.7%;pregnancyin8cases(20.5%
7、)・ConclusionBy2yearsoffollow-upobservation,interventionofadenomyosisintheuterusandfertilitypreserved,whilestillwithlesstraumaandrapidreliefofsymptoms,lessrecurreneeandsoon.[Keywords]Adenomyosis;Intervention;Follow-up子宫腺肌症又称内在子宫内膜异位症,是由于子宫内膜基底层侵入子宫肌层引起的一种良性病变。近年来子宫腺肌症的发
8、病率有所上升,其发病年龄又有下降趋势[1,2]。介入治疗避免了传统采用的激素疗法和手术切除的不良后果,是近些年来子宫腺肌症治疗中备受关注的方法。笔者所在医院从2007年1月开始对39例子宫腺肌症患者进行了介入治疗并长期随访(2年),取