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1、富硒浓缩六味地黄丸治疗精液异常男性不育临床观察王松林杨红波刘文兰S超【摘要】冃的：观察富硒浓缩六味地黄丸对肾阴或肾精亏虚型精液异常男性不育患者精液质量、激素水平的影响。方法：160例符合纳入标准的患者等分为治疗组、对照组。治疗组给予富硒浓缩六味地黄丸(9g/次，tid),对照组给予左卡尼汀口服液(1支/次，Bid),共治疗12周；观察治疗前后两组患者精液参数、男性激素水平的变化；所得数据采用SPSS17.0软件进行统计学分析。结果：治疗组临床有效率为86.9%,对照组临床有效率为66.8%,治疗组痊愈率、显效率、总有效率优于对照组(P<0.01)；治疗组精液量、精子密
2、度、精子活力百分率、液化时间治疗前后有较显著变(P<0.01),与对照组比较在提高精液量、精子密度、液化时间方面差异有统计学意义(P〈0.05),但在改善A及A+B级精子百分率方面无统计学意义(P>0.o5)；治疗组在治疗前后比较T水平变化显著(P<0.01),LH变化(P<0.05)有统计学差异。H、PRL.E2变化不显著，无统计学差异(P>0.05)。对照组各组激素水平变化无统计学意义(P>0.05)。结论：富硒浓缩六味地黄丸在提高精液量、精子密度、精子活动率、液化情况等方面显示了很好的临床作用，同时对提高体内睾酮、促黄体生成素水平也有一定的作用。【关键词】富硒浓
3、缩六味地黄丸；精液异常；肾精亏虚;肾阴虚EfectsofZuoguiPillonthetreatmentofseminalabnormalityL/Haisong,HANLiang,ZHOU,WangLin,DangJinDongzhimenHospitai,BeijingUniversityofTraditionalChineseMedicine,Beting100700,China[Abstract]objectives：ToobservetheclinicalefectsofZuoguiPillonsemenqualityandhormonelevelinthe
4、patientswithseminalabnonnalitycausedbykidneyyinordeficiencyofkidney一essenee.Methods：Onehundredandsixtycasesmeetingtheinclusivecriteriawereequallydividedintothetreatmentgroupandthecontrolgroup・ThetreatmentgroupweretreatedbyZuoguiPill(9geachtime,tid)；thecontrolgroupweretreatedbyoralLcarni
5、tine(1ampouleeachtime,Bid)・Bothgroupsre•ceivedtreatmentfor12weeks・Thenthechangeofthesemenparametersandthehormonelevelswerecomparedbeforeandafterthetreatment・Finally.alltheobtaineddatawereanalyzedwithSPSS17・Ostatisticalsoftware・ResuIts：Theclinicaleffectiverateforthetreatmentgroupwas86.9%
6、,andtherateforthecontrolgroupwas66.8%・Therecoveryrate,thesymptomimprove一mentrateandthetotaleficacyrateinthetreatmentgroupwereallsignificantlyhigherthanthoseinthecontrolgroup(P<0.01)・Therewassignificantchangesinspermvolume,spermdensity,mobilerateandliquefactioninthetreatmentgroup(P<0.01)
7、・Theefectsweresignificantinspermvolume,spermdensityandliquefaction(P〈0・05),butnotstatisticallysignificantinAandA+Bdegreespermiepercentage(P>0.05)・ThechangesofTlevel(P<0・01)andLH(P<0.05)weresignificantinthetreatmentgroup,butnosignificantdiferenceswerefoundinthechangesofFSH,PRLan
