资源描述：
《急性创伤性血胸凝血功能异常的临床研究》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、急性创伤性血胸凝血功能异當的临床研究作者：土良馥，陈自力,熊建生，黄强，毛洪涛单位：解放军笫94医院ICU,江西南昌330002【摘要】目的探讨急性创伤性血胸患者的凝血功能变化特点及与出血量严重程度、预后的关系。方法①将126例急性创伤性血胸患者分为小量、中量、大量3组，测定患者入院当时、24h、及72h的血浆凝血酶原吋间(PT)、活化部分凝血活酶吋间(APTT)、纤维蛋白原(FIB)、血小板(BPC)值，并与43例健康对照组比较。②入院、24h、72h将各组血胸的凝血指标异常发生情况进行比较。结果①各型•血胸中入院
2、吋PT、APTT、FIB、BPC均有异常,随着胸腔出血量增大，PT、APTT均升高，FIB、BPC降低。②入院24h各组血胸的凝血指标异常发牛率无明显差异。③入院72h大量血胸组患者的凝血指标显常发牛率和中、小量血胸组相比有明显差界。结论小量血胸患者的凝血功能无异常改变，中、人量血胸患者的凝血功能异常，且与血胸量程度相关，大量血胸组患者的入院72h凝血指标异常发生率艶著提高，可为急性创伤性血胸的治疗和判断预后提供依据。【关键词】血胸;凝血功能;严重程度;预后Clinicalstudyofbloodcoagulatio
3、nandfibrinolysininacutetraumatichemothoraxWANGLiangfu,CHENZili,XIONGJiansheng,HUANGQiang,MAOHongtao(DepartmentofICU,the94thHospitalofPLA,Nanchang330002,Jiangxi,China)[Abstract]ObjectiveToinvestigatethecharacteristicsofbloodcoagulationandfibrinolysininacutetraum
4、atichemothoraxandtoevaluateitsrelationshipwithbleedingvolumeandprognosis.Methods①Divided126casesintothreegroups:alittleamount,mediumamountandthelargeamount,accordingtothebleedingvolumeofacutetraumatichemothorax・Detectedthelevelsofplasmaprothrombintime(PT),activ
5、epartplasmaprothrombin(APTT),Fibrinogen(FIB),andthrombocyte(BPC)atpatientsregisteredthehospital,after24hoursand72hoursrespectively,andcomparedwiththehealthycontrolgroup・②Comparedtheabnormallevelofthecoagulantindexbetween24hoursand72hoursgroup.Results①PT,APTT,FI
6、BandBPCwereabnormalinallkindsofacutetraumatichemothorax,whenthepatientsregisteredthehospital.Morebleedingvoulum,higherlevelofPTandAPTTwerefound,butreverseofthelevelofFIBandBPC・②Patientsenrolledinthe24hoursgrouphadnosignificantdifferenceintherateoftheabnormalcoa
7、gulationparameters.(3)Thereweregreatchangesbetweenthelargeamountandtheothergroups.ConclusionTherewereobviouschangesofPT,APTT,FIBandBPCinthegroupsofmediumandlargeamountbleeding,exceptthelittleamountgroup,andthechangeswererelatedtothevolumeofbleeding.Forthecoagul
8、ationparameterswaselevatedsignificantlyinthepatientswithlargeamounthemothorax(after72hours),PT,APTT,FIBandBPCcouldbegoodindexestojudgetheprognosisofpatientssufferedfromacute
