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1、奥扎格雷钠联合银杏达莫治疗进展性缺血性脑卒中疗效观察[摘耍]冃的观察奥扎格雷钠联合银杏达莫治疗进展性缺血性脑卒中疗效。方法选择150例发病在12〜48h,病悄•呈进行性加重的进展性缺血性脑卒中患者,随机分为三组:银杏达莫治疗组,奥扎格雷钠治疗组,奥扎格雷钠联合银杏达莫治疗组;1个疗程后作疗效判定。结果1个疗程后奥扎格雷钠组总有效率82.0%,联合用药组总有效率90.0%,明显高丁•银杏达莫组,治疗前后血液流变学亦有显著的变化。结论奥扎格雷钠能有效的治疗进展性缺血性脑卒中,与银杏达莫联合使用具有协同作用。[关键词]奥扎格雷钠;银杏达莫;
2、缺血性脑卒中;联合[中图分类号]R743.3[文献标识码]A[文章编号]1673-9701(2010)01-41-03CombinationofSodiumOzagrelforInjectionwithGinkgoLeafExtractandDipyridamoleAgentinTreatmentofProgressiveCerebralArterialThrombosisLIANGYanWUYongLIANGHanzhouDepartmentofNeurology,GaozhouCityPeople"sHospital,Gaozho
3、u525200,China[Abstract]ObjectiveToobservethecurativeeffectofSodiumOzagrelforinjectioncombinedwithGinkgoLeafExtractandDipyridamoleagentinthetreatmentofprogressivecerebralarterialthrombosis・McthodsWcselected150caseswithprogressivecerebralarterialthrombosisthathappenedfrom
4、12hto48handwhichshowedprogressiveaggravation,andrandomlydividedtheminto3groups:groupofSodiumOzagrelforinjection,groupofGinkgoLeafExtractandDipyridamoleagent,andgroupofSodiumOzagrelforinjectioncombinedwithGinkgoLeafExtractandDipyridamoleagont.Anobservationwasmadeonthecha
5、ngesinthebloodhemorrheologyandthecurativeeffectofthethreegroupsafteronetreatmentcourse.ResultsAfteronecourseoftreatment,thetotaleffectiverateofthegroupofSodiumOzagrelforinjectionandthegroupofSodiumOzagrelforinjectioncombinedwithGinkgoLeafExtractandDipyridamoleagentwas82
6、・0%and90・0%respectively,muchhigherthanthatofthegroupofGinkgoLeafExtractandDipyridamoleagent.Thechangeofthebloodhemorrheologybeforeandaftertreatmentwassignificant・ConclusionSodiumOzagrelforinjectioniseffectiveinthetreatmentofprogressivecerebralarterialthrombosis,andSodiu
7、mOzagrelforinjectioncombinedwithGinkgoLeafExtractandDipyridamoleagenthasasynergisticeffectonthedisease.[Keywords]SodiumOzagrelforinjection;GinkgoLeafExtractandDipyridamoleagent;Cerebralarterialthrombosis;Combination缺血性脑血管疾病占所有脑血管疾病70%〜85%,致残和致死率均较高。溶栓治疗已被认为是最有效的方法,但有很多局
8、限性,在基层医院和交通不发达的地方较难开展。对于起病6h以上,病灶仍继续发展的进展性脑卒小尚未有较为有效的治疗方法。我院于2007年1月〜2009年6月采用奥扎格雷钠联合银杏达莫治疗方法,取得了一定效果,现报道如下。1资