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1、甲状腺结节的临床和病理特点分析【摘要】目的探讨甲状腺结节性病变患者的临床病理特点。方法对203例甲状腺结节性病变患者的临床资料予以回顾性分析,观察其临床病理特点。结果203例患者中男、女比例为1:2・08(男66例,女137例);其中良性肿瘤161例(79.31%);恶性肿瘤42例(20.69%),良性与恶性比例为3.83:1;良性结节中以结节性甲状腺肿与甲状腺腺瘤为主,共有130例,占肿瘤结节的80.75%[(81+49)/161];恶性肿瘤中以乳头状癌为主,共有31例,占恶性肿瘤的73.81%[(24+7)/42],其中微小型乳头状癌(
2、直径不足1cm)7例,占乳头状癌的22.58%,髓样癌6例,滤泡癌3例,弥漫大B细胞淋巴瘤2例。结论临床通过病理检查可以确定甲状腺结节的性质与病理特征,镜下仔细观察并结合临床诸多因素综合考虑,对该病的病理诊断、治疗以及预后均具积极作用。【关键词】甲状腺结节;病理诊断;良性结节DOI:10.14163/j.cnki.11-5547/r.2015.19.007ClinicalandpathologicalcharacteristicsanalysisofthyroidnoduleGUOJian,ZHANGShi-hao,YANLi-ya,eta
3、l.GuangdongDongguanCityDalangHospital,Dongguan523770,China[Abstract]ObjectiveToinvestigateclinicalpathologicalcharacteristicsofthyroidnodulelesionpatients・MethodsCliniceddataof203thyroidnodulelesionpatientswereretrospectivelyanalyzed.Theirclinicalpathologicalcharacteristic
4、swereobserved.ResultsGenderdistributionwas1:2.08(66malecasesand137femalecases)in203patients.Therewere161caseswithbenigntumor(79.31%)and42caseswithmalignanttumor(20.69%),witharatioof3.83:1.Benignnodulemainlyincludednodulargoiterandthyroidadenomaintotally130cases,accountingf
5、or80.75%[(81+49)/161].Malignanttumormainlyineludedpapillarycarcinomain31cases,accountingfor73.81%[(24+7)/42]・Therewere7caseswithmicrominiaturepapi1larycareinoma(diameter1essthan1cm),accountingfor22.58%,6caseswithmedullarycarcinoma,3caseswithfollicularcarcinoma,and2caseswit
6、hdiffuselargeBcelllymphoma.ConclusionClinicalpathologicalexaminationcanidentifythenatureandpathologicalcharacteristicsofthyroidnodule.Combinationofcloselymicroscopicobservationandcomprehensiveconsiderationofclinicalfactorscanprovidepositiveeffectsforpathologicaldiagnosis,t
7、reatmentandpreventionofthedisease.[Keywords]Thyroidnodule;Pathologicaldiagnosis;Benignnodule甲状腺内的肿块统称为甲状腺结节,是最常见的一种甲状腺病症,炎症、肿瘤、自身免疫异常和退行性变等病因均可表现为甲状腺结节[1,2]。该病有良性与恶性之分,但其临床发病普遍较为隐匿且无特殊表现,有的良性结节生长迅速类似恶性肿瘤,而部分恶性结节却生长缓慢而如同良性结节,因此,早期有效辨析结节的性质有利于患者的治疗与预后,应用病理学诊断是当前确诊该病最可靠的一种辨析方
8、式。本次对东莞市大朗医院和东莞市人民医院收治的203例甲状腺结节患者的临床资料给予了回顾性分析,旨在观察该病的临床病理特征,现将结果报告如下。1资料与方法1.1一般资料将东莞市大