补肾活血方联合雌孕激素治疗卵巢早衰效果分析

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1、补肾活血方联合雌孕激素治疗卵巢早衰效果分析doi：10.3969/j.issn.1007-614x.2014.16.60摘要目的：观察雌孕激素结合补肾活血方对卵巢早衰患者的治疗效果。方法：收治卵巢早衰患者179例，随机分为研究组91例和对照组88例。研究组采用雌孕激素结合补肾活血方联合治疗，对照组只用雌孕激素治疗，观察比较两组患者的疗效、各项生化指标及治疗后症状积分。结果:治疗后，研究组在盗汗、潮热、阴道干涩等方面的症状改善比对照组明显,有效率93.41%,高于对照组的81.81%,差异具有统计学意义（P<0.05）o研究组FSII、LIKINH-B等指标改善比对照组

2、明显，差异具有统计学意义（P<0.05）o结论：雌孕激素与补肾活血方相结合治疗卵巢早衰的效果优于常规单雌孕激素治疗，值得临床研究推广。关键词雌孕激素补肾活血方卵巢早衰EffectanalysisofBuShenHuoXuedecoctioncombinedwithestrogenandprogesteronehormonesinthetreatmentofprematureovarianfailureZhouYanqiDepartmentofObstetricsandGynecology,thePeople'sHospitalAffiliatedtoJiangsuUn

3、iversity,212002AbstractObjective：ToobservethetreatmenteffectofestrogenandprogesteronehormonescombinedwithBuShenHuoXuedecoctioninthetreatmentofpatientswithprematureovarianfailure.Methods：179caseswithprematureovarianfa订urewereselected.Theywererandomlydividedintothestudygroupwith91casesand

4、thecontrolgroupwith88cases.ThestudygroupweretreatedwithestrogenandprogesteronehormonescombinedwithBuShenIIuoXuedecoction.Thecontrolgroupweretreatedwithonlyestrogenandprogesteronehormonestreatment.Thecurativeeffects,biochemicalindicesandtreatmentsymptomscoresofthetwogroupswereobserved.Re

5、suIts：Afterthetreatment,thesymptomsinthesweating,hotflashes,vaginaldrynessandotheraspectsofthestudygroupwereimprovedobviouslythanthoseofthecontrolgroup.Theeffectiverateofthestudygroupwas93.41%,anditwashigherthan81.81%ofthecontrolgroup.Thedifferencewasstatistical1ysignificant(P<0.05).The

6、FSH,LH,INH-Bandotherindicatorsofthestudygroupwereimprovedobviouslythanthoseofthecontrolgroup.Therehadasignificantdifferenee(P<0.05).Conclusion:TheeffectofestrogenandprogesteronehormonescombinedwithBuShenHuoXuedecoctioninthetreatmentofprematureovarianfailureisbetterthanthatofconventional

7、singlehormonetreatment・Itisworthyofclinicalresearch・KeywordsEstrogenandprogesteronehormones；BuShenIIuoXuedecoction；Prematureovarianfailure卵巢早衰（P（）F）是指卵巢功能非止常消耗，提前功能耗尽的疾病，近年来发病率逐渐增高。其原因与遗传因素、抵抗力下降或手术等有关，常表现为闭经过早、雌激素过少、促性腺激素增多等，具有面色潮红、盗汗、阴道干涩、性欲低下等症状［1-2］o当前常用的治疗方案是雌孕激素抵抗，具有较好的疗效