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1、注意缺陷多动障碍儿童眼动抑制缺陷对照探究【摘要】目的：探讨注意缺陷多动障碍(AttentionDeficitHyperactivityDisorder,ADHD)儿童在抑制性眼动任务中的反应特征。方法:采用注视、主动眼动及反向眼动任务对21例ADHD儿童和21例正常对照儿童进行评估。结果：(1)注视任务中,ADHD组侵入性眼跳数目高于对照组［无分心条件:(12.67±12.28)vs.(6.38±6.95),P=0.040；分心条件：(16.91±10,00)vs.(11.29±5.99),P-0.030］；(2)主动眼动任务中，两组儿童眼跳参数差异无统计学意义；(3)反向眼动任务中，A
2、DHD组眼跳方向错误率高于对照组［间隔条件:(68.14±17.85)%vs.(54.10±20.22)%,P=0.020；重叠条件:(62.49±17.54)%vs.(49.27±17.21)%,P=0.020］。结论：注意缺陷多动障碍儿童眼动抑制能力存在缺陷，推测可能是由于注意缺陷多动障碍儿童具有异常的额叶-纹状体结构和/或功能所致。【关键词】注意缺陷多动障碍;眼动任务;抑制；眼跳；病例对照研究中图分类号:R749.94文献标识码：A文章编号:1000-6729(2010)001-0038-05doi：10.3969/j.issn.1000-6729.2010.01.009Inhib
3、itorydeficitsofoculomotorbehaviorinchildrenwithattentiondeficithyperactivitydisorderCHENQiangl,2,JINGJinl,YANGWen-Han❷1^lDepartmentofMaternalandChildHeaIth,SchoolofPublicHeaIth,SunYat-senUniversity,Guangzhou510080,China^2DepartmentofChildPsychologicalBehavior,ZhuhaiMaternalandChildHealth"sHospita
4、l,Zhuhai519000,GuangdongProvince,ChinaCorrespondingauthor：JINGJin,E-mail：jingjin@mai1.sysu.省略【Abstract】Objective：Toexaminethecharacteristicsofoculomotorinhibitionaboutchildrenwithattentiondeficithyperactivitydisorder(ADHD).Methods：Twenty-onechildrenwithADHDaccordingtotheDiagnosticandStatisticalMa
5、nualofMentalDisorder,4thedition(DSMTV)and21matchedcontrolswereadministeredwithfixation,prosaccadeandantisaccadetasks・ResuIts：(1)Inthefixationtask,thechildrenwithADHDdemonstratedsignificantlymoreintrusivesaccadeerrorsthanthecontrolsineitherconditionwithdistractorsorwithoutdistractors[nodistractors
6、：(12.67±12.28)vs.(6.38±6.95),P二0.040；distractors：(16.91±10.00)vs.(11.29±5.99),P=0.030]・(2)Intheprosaccadetask,therewerenosignificantdifferencesfoundbetweengroupsinsaccadicparameters,ineithergapconditionoroverlapcondition.(3)Inantisaccadetask,thedirectionerrorratesoftheADHDgroupineithergapconditio
7、noroverlapcondition,werebothhigherthanthatofthecontrolgroup[gap：(68.14±17.85)%vs.(54.10±20.22)%,P=0.020；overlap：(62.49±17.54)%vs.(49.27±17.21)%,P=0.020].Conclusion：Itsuggeststhatthereisanabnormalityoftheoculomotorinhib
