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1、临床医学论文•妊娠合并甲状腺功能亢进症67例临床分析【摘要】目的:探讨妊娠合并甲状腺功能亢进的临床特点及处理原则。方法:回顾性分析我院与南华大学附属南华医院11年间妊娠合并中状腺功能亢进67例患者的资料，按照正规治疗与否分为对照组30例和治疗组37例。结果:①治疗组患者甲状腺激索水平勻对照组比较差异有统计学意义(P<0.05)。②妊娠结局:两组新生儿平均体重、1分钟Apgar评分比较，差异有统计学意义(P<0.05)。③分娩方式:治疗组患者阴道分娩19例,剖宫产18例;对照组患者经阴道产钳助娩1例,剖宫产
2、19例，阴道分娩10例。④并发症:对照组中10例患者合并妊娠期高血压疾病(其中子痫前期4例),6例患者合并心功能不全,2例患者发生甲状腺危象。治疗组中1例患者同时合并子痫前期。结论:①孕期病情得到控制的患者可视同正常妊娠；②产时及产后防止心功能不全和甲状腺危象;③中、重度妊娠合并甲状腺功能亢进症适当放宽剖宫产指征。妊娠合并甲状腺功能亢进症常危及母婴健康,为降低母儿风险,孕前需很好地控制病情,孕期密切监控，合理治疗。【关键词】妊娠;甲状腺功能亢进症;治疗[AbstracI】Objective:Toevalu
3、atetheclinicalcharacteristcsandtreatmentofhyperthyroidisminpregnaney.Methods:Wereviewedmedicalrecordsof67caseswithhyperthyroidismduringpregnancyatourhospitaiandthenanhuahospitalofnanhuauniversityoveraperiodof11years.67casesweredividedintotwogroupsaccordin
4、gtotheirtherapyrecords,onegrouphas37caseswithstandardtreatment,theotherhas30caseswithoutstandardtreatmentascontrolgroup・Results:1.Comparedwithstandardtherapygroup,theserumlevelsofFT4/FT3innon-standardtherapygroupweresignificantlyhigherandthescrumlevelsofT
5、SHweresignificantly1ower(P<0.01).2PregnantOutcome:ThemeannewbornweightandoneminuteApgarscoreafterdeliveryoftencasesincontrolgroupweresignificantly1owerthanthatofthestandardtherapygroup(P<0.05).3.Deliveryway:Inthecontrolgroup,leasewasdeliveredwithforceps,9
6、casesweredeliveredbyCaesareansection.Inthestandardtherapygroup,19easesdeliveredthroughvagina,18casesweredeliveredbycaesarean-section.3.Complications:Inthecontrolgroup,10caseswereincorporatedwithpregnaney・inducedhypertention(4casespre・eclampsia).6caseswith
7、cardiacfailure,2caseswiththyrointoxication.Inthestandardtreatmentgroup,only1casewascomplicatedwithprccclampsia・Conclusions:1・MiIdhyperthyroidismpatientsduringpregnancyshouldbemanagedasnormaliftreatedproperlyandprompt1y.2・Heartfailureandthyrointoxicationmu
8、stbepreventedinlaborandafterdelivery.3・Pregnancycombinedwithhyperthyroidismoftenendangersmaternalandneonatalhealth.Therefore,forreducingtherisks,beforepregnancy,thepatients5conditionsshouldbewellcontrolled;duringpre
