前庭阵发症的临床特征及治疗

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1、NVC的患者患者共24例(51%),37耳，两组NVC阳性率相比差异有统计学意义(咒2=13.713,严0.05)。所有VP患者治疗后1个月、2个月、3个月分别与治疗前相比，眩晕发作频率明显降低(t=12.480,严0.05；L10.616,p<0.05；t=11.601,pv0.05),眩晕的严重程度亦明显好转(t=16.835,p<0.05；t=16.527,p<0.05；t=17.819,p<0.05)o结论：1.VP常以反复发作的短暂性眩晕为主要临床表现，发病前常有头位或体位变动等诱发因素；

2、ABR常有I・III波峰间期的延长，MRI常提示NVC现象；小剂量抗癫痫药物能有效控制眩晕症状。2.ABR及MRI能够帮助诊断VP,但临床诊断不能仅依赖这些辅助检查，仍应以依靠病史及排除诊断为主，抗癫痫药物试验性治疗在诊断中有重要意义。关键词：前庭阵发症；听性脑干反应；磁共振成像；抗癫痫药物AbstractClinicalFeaturesandMedicalTreatmentsofVestibularParoxysmiaPostgraduateFankaihuiTutorLuweiDepartmen

3、tofOtologyTheFirstAffiliatedHospitalofZhengzhouUniversityZhengzhouHenan450052AbstractObjective:Toexploretheclinicalfeaturesofvestibularparoxysmia(VP)andevaluatethesignificanceofaudiologyandimaginginthediagnosisofVPandthetherapeuticefficacyofantiepolept

4、ics・Methods:41patientswithVPinoutpatientwereperformedwithphysicalexamination,audiologyexaminationandMRI.Andthelatterwasappliedon47patientswithsuddenhearinglosstojudgeiftherewasneurovascularcompression(NVC)andcomparethedifferencesoftheresultsbetweentwog

5、roups.Thevisualanaloguescale(VAS)shouldbeusedtoevaluatethecontrolofvertigosymptomsaboutVPpatientsbeforeandafterthetreatmentofantiepileptics.Results:41patientswithVPincluded16malepatientsand25femaleones,theratioofmaletofemalewas1:1.56andtheaverageagewas

6、51.7±11.7years.Themainclinicalsymptomwasabriefspellofvertigoandthemajorityofpatientshadapredisposingfactorbeforeonsct.In33paticnts(80%)thcattacksoccurredwhenheadinAbstractorbodypositionchanged,whereas25paticnts(68%)wcrcprecipitatedatrest.In23patients(5

7、6%)threeminuteshyperventilationcouldinducevertigo.Theauditorybrainstemresponse(ABR)wasabnormalin30patients(73%),25patientsamongthemhadtheinterpeaklatencyofwaveI-1IIprolongedthan2・2ms.36patientswith50earsexistedNVCinVPgroup.while24patientswith31earswere

8、foundNVCinsuddenhearinglossgroup.Thedifferenceoftwogroupswasstatisticallysignificant.Afteronemonth>twomonthsandthreemonthsofthemedicinetreatment,therewasasignificantreductionrespectivelyintheattackfrequencyandintensity.Conclusions:1.The