欢迎来到天天文库
浏览记录
ID:43494726
大小:417.71 KB
页数:6页
时间:2019-10-08
《细胞因子释放综合征的发生机制和防治策略》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据壁遁婴塞皇堕塞!Q!!至!旦笙!!鲞笙!塑堡塑!竺旦!!!墅!塑i垦!迥!!!!!翌!翌!Q!!!!塑:望:盟!:兰[28]VallierL,TouboulT,ChngZ,eta1.Earlycellfatedecisionsofhumanembryonicstemceilsandmouseepiblaststemcellsayecontrolledbythesalnesignallingpathways[J].PLoSOne,2009,4(6):e6082.129JZhangP,LiJ,Tanz,eta1.Short—termBMP--4treatmentinitiatesme
2、soderminductioninhumanembryonicstemcells[J].Blood,2008,11l(4):1933—1941.130JHuY,MintzA,ShahSR。eta1.TheFGFR/MEK/ERK/brachyurypathwayiscriticalforchordomacellgrowthandsurvival[J].Carcinogenesis,2014,35(7):1491—1499.131JIAiFoccaC,CohenJR,FernandoRI,eta1.AnautocrineloopbetweenTGF—betalandthetranscn"p
3、tionfactorbrachyurycontrolsthetransitionofhumancarcinomacellsintoamesenchymalphenotype·135·[J].MolCancerTher,2013,12(9):1805—1815.[32]HamiltonDH,PalenaC,LitzingerMT,eta1.Immunologicaltargetingoftuntorcellsundergoingallepithelial—mesenchymaltransitionviaarecombinantbrachyury—yeastvaccine[J].Oncota
4、rget,2013,4(10):1777—1790.[33]KitamuraY,SasakiH,KimuraT,eta1.Molecularandclinicalriskfactorsforrecurrenceofskullbaseehordomas:gainonchromosome2p,expressionofbrachyury,andlackofirradiationnegativelycorrelatewithpatientprognosislJJ.JNeuropatholExpNeural,2013.72(9):816—823.细胞因子释放综合征的发生机制和防治策略钱军周俊东邹志
5、宏综述(收稿13期:2014-07.16)(本文编辑:郎华校对:陈磊)【摘要】生物治疗是近年来肿瘤临床研究中的热点,应用日益广泛,一些独特的不良反应也逐渐被认识。细胞因子释放综合征是一种可能危及生命的不良反应,文章就细胞因子释放综合征的发生机制、预防和治疗进展进行综述。【关键词】细胞因子;细胞因子释放综合征;生物治疗MechanismsandtreatmentofcytokinereleasesyndromeQ协Jun,ZhouJundong,ZouZhihong.TumorDiagnosisandTreatmentCenter,SazhouMunicipalHospital,Suzho
6、uCancerCenteGSuzhou215001,ChinaCorrespondingauthor:QianJu以Email:byqj@medmail.com.en【Abstract】Biologicaltherapyforcatlcerhasbecameahighpointinrecentyears.Ithasbeenwidelyappliedinclinicalfield.Managementoftheiruniquetoxicitiesbecomesmoreandmoreimportant.Cytokinereleasesyndrome(CRS)isapotentiallylif
7、e·threateningtoxicity.ThisreviewdiscussesthemechanismsthatcauseCRS,andnewdevelopmentsinthepreventionandtreatmentofCRS.【Keywords】Cytokine;Cytokinereleasesyndrome;Biologicaltherapy早在20世纪80年代,生物治疗就被誉为继手术、放疗和化疗之后的第四大肿瘤治疗手段
此文档下载收益归作者所有