心脏移植和机械型循环辅助（英文）

《心脏移植和机械型循环辅助（英文）》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、CardiacTransplantationandMechanicalCirculatorySupportAndrewBoyle,MDAssociateProfessorofMedicineMedicalDirectorofHeartFailure,CardiacTransplantation,andMechanicalCirculatorySupportDivisionofCardiologyUniversityofMinnesotaMetabolicStressTestingManciniDetal.

2、Circulation1991;83:778-786.Group1:peakVO2<14Group2:peakVO2>14Group3:rejectedforOHTxAGEDISTRIBUTIONOFHEARTRECIPIENTS(1/1982-6/2003)%ofTransplantsJHeartLungTranspl.2004;23:796-803.DIAGNOSISINADULTHEARTTRANSPLANTSHEARTTRANSPLANTATIONKaplan-MeierSurvival(1/19

3、82-6/2006)JHeartLungTransplant2008;27:937-983.UMNCardiacTransplantSurvivalNUMBEROFHEARTTRANSPLANTSREPORTEDBYYEARJHeartLungTransplant2008;27:937-983HEARTTRANSPLANTS:DonorAgebyYearofTransplantJHeartLungTranspl.2004;23:796-803.DescriptionofUNOSStatusLevelsSt

4、atusIARHCinplaceand:twoormoreinotropesregardlessofdoseIVmilrinoneatleast0.5mcg/kg/minIVdobutamineatleast7.5mcg/kg/min30daysfollowingmedicalstabilizationafterVADimplantationStatusIBinotrope-dependentLVADnotmeetingcriteriaforIAstatusNoadvantageforbeinghospi

5、talizedStatusIINotinotrope-dependentandnoVADPriorityonUNOSlistbasedonstatuslevelanddurationoftimeinthatstatuslevelNocreditgivenfortimeatalowerstatuslevelStevensonLWetal.Circulation2003;108:492-7.InotropicTherapyforEnd-StageHeartFailureUniversityofMinneso

6、taVADImplantsHeartMateIIPulsatilevsContinuousFlowLVADsPulsatile/VolumeDisplacementContinuous/RotaryHeartMateIIasBTTMillerL,BoyleA,etal.NEJM2007;357:893.HeartMateIIBTTClinicalTrialAdverseEventRatesAdverseEventHMII(62ptyrs)(n=133)HMVE1(86ptyrs)(n=280)%reduc

7、tionBleedingrequiringsurgery0.781.4747Percutaneousleadinfection0.373.4989Stroke0.190.4457Non-strokeneurological0.260.6761RVfailurerequiringRVAD0.080.3073Events/PatientYear1FrazierOH,etal.JThorCVSurg2001MillerL,JohnR,BoyleA,etal.NEJM2007;357:893.HMIIasBTTi

8、nWomenOutcomesatoneyearPamboukianS,BoyleA,etal.Circulation.2008;118:S-1016VentrAssistasBridgetoTransplantVentrAssistComponentsImplantablebloodpumpPoweredviapercutaneousleadControllerlogsparameters&alarmsBatteryorAC