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《A National Cancer Data BaseReport on 53,856 Cases ofThyroid Carcinoma Treated inthe U.S., 1985–1995国家癌症数据库 53856例报告 甲状腺癌的治疗 美国,1985—1995》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、2638COMMUNICATIONANationalCancerDataBaseTheAmericanCollegeofReporton53,856CasesofSurgeonsCommissiononCancerandtheAmericanThyroidCarcinomaTreatedinCancerSocietytheU.S.,1985±19951ScottA.Hundahl,M.D.2IrvinD.Fleming,M.D.3AmyM.Fremgen,Ph.D.3HermanR.Menck,M.B.
2、A.1DepartmentofSurgery,TheQueen'sMedicalCenter,Honolulu,Hawaii.2DepartmentofSurgery,UniversityofTennesseeCenterforHealthSciences,Memphis,Tennessee.3NationalCancerDataBase,AmericanCollegeofSurgeons,Chicago,Illinois.BACKGROUND.TheNationalCancerDataBase(NCD
3、B)representsanationalelec-tronicregistrysystemnowcapturingnearly60%ofincidentcancersintheU.S.IncombinationwithotherCommissiononCancerprograms,theNCDBoffersaworkingexampleofvoluntary,accurate,cost-effectiveªoutcomesmanagementºonabothalocalandnationalscale
4、.Inaddition,itisofparticularvalueincapturingclinicalinformationconcerningrarecancers,suchasthoseofthethyroid.METHODS.Fortheaccessionyears1985±1995,NCDBcaptureddemographic,pat-terns-of-care,stage,treatment,andoutcomeinformationforaconveniencesam-pleof53,8
5、56thyroidcarcinomacases(1%oftotalNCDBcases).Thisarticlefocusesonoverall10-yearrelativesurvivalandAmericanJointCommitteeonCancer(AJCC)(3rd/4thedition)stage-strati®ed5-yearrelativesurvivalforeachhistologictypeofthyroidcarcinoma.Carepatternsalsoarediscussed
6、.RESULTS.The10-yearoverallrelativesurvivalratesforU.S.patientswithpapillary,follicular,HuÈrthlecell,medullary,andundifferentiated/anaplasticcarcinomawas93%,85%,76%,75%,and14%,respectively.Forpapillaryandfollicularneoplasms,currentAJCCstagingfailedtodiscr
7、iminatebetweenpatientswithStageIandIIdiseaseat5years.Totalthyroidectomy6lymphnodesampling/dissectionrepresentedthedominantmethodofsurgicaltreatmentrenderedtopatientswithpapillaryandfollicularneoplasms.Approximately38%ofsuchpatientsreceiveadjuvantiodine-1
8、31ablation/therapy.At5years,variationinsurgicaltreatment(i.e.,lobectomyvs.moreextensivesurgery)failedtotranslateintocompellingdifferencesinsurvivalforanysubgroupwithpapillaryorfollicularcarcinoma,butlongerfollow-upisrequir