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1、ReviewofApplicationofCodingTheoryinGeneticSequenceAnalysisX.H.Wang',R.S.H.Istepanian',Y.H.Song2andE.E.May3'SchoolofComputingandInformationSystems,KingstonUniversity,KingstonuponThames,SurreyKTllLQ,UK*Dept.ofElectronicandComputerEng.,BrunelUniversity,UK'SandiaNationalLaboratories,ComputationalBiolog
2、yDepartment,P.O.Box5800,Albuquerque,NM87185Abstract-Applyingcodingtheoryingeneticsequenceanalysisribosomalsubunitbindstothecomplex,andthereactionsofisanewresearchareafortheinformationtheoryinbiology.IthasthepotentioaltohelpthebiologisttounderstandthenatureofthelivingorganismsandfindthesolutionstoDN
3、Acomputations.Afteranintroductionofthebiology,thispaperreviewedtheapplicationofcodingtheory,especiallyerror,controltheory,insequenceanalysis.Fromthereview,thedmabacksofthepresentapplicationshavebeenidentifiedandapossiblesolutiontotheproblemhasbeengiven.I.INTRODUCTIONTheinformationtheorywasdeveloped
4、byShannontotransmitelectronicsignals[11.Itasintroducedintobiologicalworldfrom1970sbyGatlin[2]andsincethenwidelyusedtoanalysethegeneticsequences.Codingtheoryisjustasubareaoftheinformationtheorywhichtranslatestheinformationbitsintotransmitteddatasysmbol.In1998,Mayintroducedtheerrorcontrolcodingingene
5、ticsequenceanalsysandspikesaFig.1Processofproteinsynthesisnewapplicationofinfromationtheoeryinsequcneanalysis[3].Inthispaper,wearegoingtoreviewtheworkoferrorcontroltheoryinsequenceanalysisandothersimilarworkstotrytoNucleicacidsaremoleculesthatdealingthespecificfindouttheprospectiveofthisapplication
6、s,theproblemofthestructureoftheproteins.Thebackboneofanucleicacidisapplicationandpossiblesolutions.madeofalternatingsugarandphosphatemoleculesbondedThepaperisarrangedasfollows.Insection2,thebiologicaltogetherinalongchain.Eachofthesugargroupsinthebackgroundisgivenforunderstandingthebasicsofthebackbo
7、neisattachedtoathirdtypeofmoleculecalledabiologicalworlds.Thenthebiologicalworldanalogstothenucleotidebase.communicationstheoryisdescribedinsection4.Section4ThegeneticinformationisstoredintheDNA(mo1eculerev