Dosage Form as Nutraceuticals

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1、Chapter2LactobacillusModelMoietyaNewEraDosageFormasNutraceuticalsandTherapeuticMediatorAbhinandanR.Patil,SunitaS.Shinde,PratikS.KakadeandJohnI.D’souzaAbstractInthiseraBacteriaaremostlyconsideredaspathogenic.Bacteriathougharepathogenicbutstillafewarefriendlyandessentialforhumangrowthandimmun

2、ity;calledasProbiotics.Lactobacillusmodelmoietyisoneofsuchprobioticbacteriumwhichwhenintroducedinsufficientcolonyservesasnewprophylaxisandcuringagent.Thiswillincreasetheinnateimmunityofhumans.Indianmarketlacksthequalityuni-strainproductoftheprobioticsasNutraceu-ticalsandasHealthenhancingdrug

3、product.Globalmarketisfullofmulti-strainmicrobesdosageform.ThebestmodetoutilizeNutraceuticalaspectofprobioticsistoconvertindryform.Thesepurifiedcolony;laterconvertedintothesoliddryformbyspraydry(JISLmini-spraydrier)technique.Starch,lactosewereusedasthermo-protectiveagentwhileheatdryingtechni

4、que.Anti-microbialscreeningscarriedoutalongwithInvitrocytotoxicitystudies.InvitrocytotoxicityscreeningevaluatedthatLactobacilluspowdershowingsanti-canceractivitynearlysameasstandarddrugwithnosideeffects.Drypowderincreasedtheshelflifeofthemicrobesthatresultedinmaintenanceofviabilityandactivi

5、ty.KeywordsLactobacillusmodelmoiety
Nutraceuticals
Probiotics
Pathogenic
Uni-strain2.1IntroductionTherearemorebacteriaintheworldtodaythanallthehumanseverborn.Mostofthemconsideredaspathogen.Aseverycoinhad,twosidesbesidesmostlybacteriaarepathogenbutstillfewarefriendlyessentialforhumangrowthan

6、dimmunity.A.R.Patil(&)
S.S.Shinde
P.S.Kakade
J.I.D’souzaDepartmentofPharmaceutics,TatyasahebKoreCollegeofPharmacy,Warananagar,Kolhapur416113,Maharashtra,Indiae-mail:arpatil.tkcp@gmail.comA.Kumar,BiotechnologyandBioforensics,ForensicandMedicalBioinformatics,11DOI:10.1007/978-981-287-050-6_2,

7、ÓTheAuthor(s)2015122LactobacillusModelMoietyaNewEraDosageFormSuchfriendlybacteriaarecalledprobiotics.Thefollowingaremicroorganismsconsideredtobehumanprobiotics:Lactobacillusspecies:Lactobacillusmodelmoiety:L.amylovorusetc.,Bifidobacteriumspecies:B.adolesc