Transition metal derivatives in organic synthesis annual survey covering the year 1974

《Transition metal derivatives in organic synthesis annual survey covering the year 1974》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、TRANSITIONMETALDERIVATIVESINORGANIC.SYNTHESISANNUALSURVEYCOVERINGTHEYEAR1974LOUISS.HEGEDUSDepartmentofChemistry,ColoradoStateUniversityFortCollins,Colorado80523(U.S.A.)CONTENTSI.GeneralComments422II.Carbon-CarbonBondFormation422A.Alkylation422B.ConjugateAddition431C.Carbonylation.4

2、35D.Oligomerization437E.Rearrangements442III.Oxidation445IV.Reduction450.V.FunctionalGroupPreparation455A.Halides455B.Amides,Nitriles456C.Amines456D.Ethers,Esters457E.Olefins458F.Heterocycles459G_Miscellaneous461462VI.Reviews422TRANSITIGNMETALDERIVATIVESINORGANICSYNTHESIS~1.GENERAL

3、COMMENTSThisannualsurveycoversthe1iteraturefor1974dealingwiththeuseoftransitionmetalintermediatesfororganicsynthetictransformations.Itisnotacomprehensivereview,butislimitedtoreportsofdiscretesystemsthatleadtoatleastmoderateyieldsoforganiccompounds,orthatallowuniqueorganictransforma

4、tions,eveniflowyieldsareobtained.Catalyticreactionsthatleadcleanlytoamajorproductanddonotinvolveextremeconditionsarealsoincluded.Thepapersinthissurveyaregroupedprimarilybyreactiontyperatherthanbyorganometallicreagent,sincethereaderislikelytobemoreinterestedintheorganictransformatio

5、neffectedthanthemetalcausingit.Specificallyexcludedarepapersdealingwithtransitionmetalcatalyzedhydrosilation,sincethesearecoveredbyanothersurveyinthisseries.Alsoexcludedarestructuralandmechanisticstudiesoforganometallicsystemsunlesstheypresentdatausefulforsyntheticapplication.Final

6、ly,reportsfromthepatentliteraturehavenotbeensurveyedsincepatentsarerarelysufficientlydetailedtoallowreproductionofthereportedresults.II.CARBON-CARBONBONDFORMINGREACTIONSA.AlkylationsOrganocupratereagentscontinuedtobeexploitedfortheirabilitytoselectivelyalkylateavarietyoforganicsubs

7、trates.OrganicdibromidesofthetypeBr-(CH2)n-Br(n=3,4,5,6,10)werew-alkylatedbyalkylGrignardreagentsandLi2CuC14toproducechainlengthenedmonobromidesin40-902yieldCl]_Theuseofmixedcupratestoallowefficientutilizationofvaluableorganolithiumreagentshasbeenmorefullydeveloped.Aconvenientprepa

8、rationofmixedcuprate[PhSCu